Article history:Received Aug 8, 2015 Revised Sep 21, 2015 Accepted Oct 23, 2015 Allergic rhinitis is inflammatory reactions mediated by immunoglobulin E, after exposure to allergens. Allergic rhinitis can be alleviated by the use of specific probiotics to confer immune effects. The specific strains used in this study were selected based on their anti-inflammatory properties and an expected in promoting a Th1 type of immune response. To review the benefits of probiotics of Lactobacillus casei in preventing allergy attacks which inhibit the production of IgE, IL-4 and in reducing the symptoms. The study design was quasi-experimental with pre and post test design. The subjects were 45 patients who had a history of allergic rhinitis and filled out the questionnaires to get the allergic symptoms. The blood samples were taken for examining the IgE and IL-4 levels then after giving milk containing probiotics for 1 month, the researcher did the same examination. The mean IgE and IL-4 levels decreased before and after probiotics supplementation from 291.88 IU /L and 22.48 pg/ml to 141.43 IU/L and 17.83 pg/ml. The result of the statistical analysis paired t-test test was p = 0.00 on IgE level and p=0,056 on IL-4 level. The allergic rhinitis symptoms decreased significantly, the patients who had persistent symptom reduced from 28 patients to 2 patients. Based on the Wilcoxon signed rank test showed a significance value of P = 0.00. Probiotics is useful in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduces the symptoms.