Clinical impact of adaptive servoventilation compared to other ventilatory modes in patients with treatment-emergent sleep apnea, central sleep apnea and Cheyne–Stokes respiration

Correia, Sílvia; Martins, Vitória; Sousa, Liliana de; Moita, Joaquim; Teixeira, F.; Santos, José Moutinho dos

doi:10.1016/j.rppnen.2014.08.005

Cited by 7 publications

(10 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a result, adaptive servoventilation is not recommended in patients with HF and predominantly central SA 28. However, the safety concern that arose from this study should not be applied to patients with SA without HF receiving CPAP therapy, since adaptive servoventilation and CPAP therapy are completely different modes of applying positive airway pressure,29, 30 and the increased mortality was only demonstrated in patients already diagnosed with HF with reduced ejection fraction 13. Interestingly, the US preventive service task force recently recommended not to screen for OSA because of insufficient evidence on benefits and harms of a screening program and, especially, because of the lack of evidence concerning the potential beneficial effect of CPAP therapy on hard outcomes 31.…”

Section: Discussionmentioning

confidence: 98%

Sleep Apnea, the Risk of Developing Heart Failure, and Potential Benefits of Continuous Positive Airway Pressure (CPAP) Therapy

Holt

Bjerre

Zareini

et al. 2018

JAHA

View full text Add to dashboard Cite

BackgroundWhether there is an association between sleep apnea (SA) and the risk of developing heart failure (HF) is unclear. Furthermore, it has never been established whether continuous positive airway pressure (CPAP) therapy can prevent development of HF. We aimed to investigate SA patients’ risk of developing HF and the association of CPAP therapy.Methods and ResultsUsing nationwide databases, the entire Danish population was followed from 2000 until 2012. patients with SA receiving and not receiving CPAP therapy were identified and compared with the background population. The primary end point was first‐time hospital contact for HF and adjusted incidence rate ratios of HF were calculated using Poisson regression models. Among 4.9 million individuals included, 40 485 developed SA during the study period (median age: 53.4 years, 78.5% men) of whom 45.2% received CPAP therapy. Crude rates of HF were increased in all patients with SA relative to the background population. In the adjusted model, the incidence rate ratios of HF were increased in the untreated SA patients of all ages, compared with the background population. Comparing the CPAP‐treated patients with SA with the untreated patients with SA showed significantly lower incidence rate ratios of HF among older patients.ConclusionsIn this nationwide cohort study, SA not treated with CPAP was associated with an increased risk of HF in patients of all ages. Use of CPAP therapy was associated with a lower risk of incident HF in patients >60 years of age, suggesting a protective effect of CPAP therapy in the elderly.

show abstract

Section: Discussionmentioning

confidence: 98%

Sleep Apnea, the Risk of Developing Heart Failure, and Potential Benefits of Continuous Positive Airway Pressure (CPAP) Therapy

Holt

Bjerre

Zareini

et al. 2018

JAHA

View full text Add to dashboard Cite

show abstract

“…However, CPAP seems to be ineffective in some patients. Correia et al [ 67 ] compared the clinical impact of adaptive servo-ventilation (ASV) with other forms of PAP in treating patients with TECSA, CSA, and Cheyne-Stokes respiration (CSR), and found that some CSA events persisted even with regular CPAP therapy. Fourteen out of 54 patients with an initial CSA diagnosis on CPAP titration night continued to meet the criteria for CSA at follow-up, and 16 of 382 patients (about 4%) not initially diagnosed with CSA developed novel CSA after 3 months of CPAP therapy.…”

Section: Treatmentmentioning

confidence: 99%

“…ASV is a novel ventilatory mode, which can provide a dynamic adjustment of inspiratory pressure support and a back-up respiratory rate. [ 67 ] ASV can alter pressure support accordingly based on a target minute ventilation calculated by measuring or estimating the respiratory output of the patient, in order to avoid central hypopnea/apnea events due to hyperventilation and associated hypocapnia [ 67 ] ; therefore, this device can provide more stabilized ventilation.…”

Section: Treatmentmentioning

confidence: 99%

“…[ 33 , 68 , 69 ] Correia et al compared the clinical impact of ASV with other forms of PAP in treating patients with TECSA, CSA, and CSR. [ 67 ] The results demonstrated that ASV is an effective treatment method for treating patients with TECSA, CSA, and CSR since it significantly decreased residual AHI. Moreover, the compliance rate was high, and long-term tolerance was also excellent.…”

Section: Treatmentmentioning

confidence: 99%

“…Several studies have analyzed the role of ASV in the treatment of TECSA and their results have shown that ASV is an excellent treatment option. [ 67 – 70 , 74 , 75 ]…”

Section: Treatmentmentioning

confidence: 99%

See 2 more Smart Citations

Treatment-emergent central sleep apnea: a unique sleep-disordered breathing

Zhang

Wang

Guo

et al. 2020

Chinese Medical Journal

View full text Add to dashboard Cite

Treatment-emergent central sleep apnea (TECSA) is a specific form of sleep-disordered breathing, characterized by the emergence or persistence of central apneas during treatment for obstructive sleep apnea. The purpose of this review was to summarize the definition, epidemiology, potential mechanisms, clinical characteristics, and treatment of TECSA. We searched for relevant articles up to January 31, 2020, in the PubMed database. The prevalence of TECSA varied widely in different studies. The potential mechanisms leading to TECSA included ventilatory control instability, low arousal threshold, activation of lung stretch receptors, and prolonged circulation time. TECSA may be a self-limited disorder in some patients and could be resolved spontaneously over time with ongoing treatment of continuous positive airway pressure (CPAP). However, central apneas persist even with the regular CPAP therapy in some patients, and new treatment approaches such as adaptive servo-ventilation may be necessary. We concluded that several questions regarding TECSA remain, despite the findings of many studies, and it is necessary to carry out large surveys with basic scientific design and clinical trials for TECSA to clarify these irregularities. Further, it will be vital to evaluate the baseline demographic and polysomnographic data of TECSA patients more carefully and comprehensively.

show abstract

Adaptive servo-ventilation and sleep quality in treatment emergent central sleep apnea and central sleep apnea in patients with heart disease and preserved ejection fraction

et al. 2018

View full text Add to dashboard Cite

show abstract

Clinical impact of adaptive servoventilation compared to other ventilatory modes in patients with treatment-emergent sleep apnea, central sleep apnea and Cheyne–Stokes respiration

Cited by 7 publications

References 17 publications

Sleep Apnea, the Risk of Developing Heart Failure, and Potential Benefits of Continuous Positive Airway Pressure (CPAP) Therapy

Sleep Apnea, the Risk of Developing Heart Failure, and Potential Benefits of Continuous Positive Airway Pressure (CPAP) Therapy

Treatment-emergent central sleep apnea: a unique sleep-disordered breathing

Adaptive servo-ventilation and sleep quality in treatment emergent central sleep apnea and central sleep apnea in patients with heart disease and preserved ejection fraction

Contact Info

Product

Resources

About