Clinical Impact of Point-of-Care Testing Using the OMNI-S Blood Gas Analyzer in a Neonatal Intensive Care Setting

Arthurs, Owen J.; Pattnayak, Santosh; Bewley, Barbara; Kelsall, W

doi:10.1097/poc.0b013e3181d2d6b0

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…Moreover, the ABL90 FLEX blood gas analyzer requires as little blood as 65 μL, which is much less than is needed for routine tests in the hospital laboratory. This makes this ABG analyzer particularly useful for neonates [ 9 ]. Similar POC testing instruments have the same advantages.…”

Section: Discussionmentioning

confidence: 99%

Analysis of Bias in Measurements of Potassium, Sodium and Hemoglobin by an Emergency Department-Based Blood Gas Analyzer Relative to Hospital Laboratory Autoanalyzer Results

Zhang

Zhao

2015

PLoS ONE

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ObjectiveThe emergency departments (EDs) of Chinese hospitals are gradually being equipped with blood gas machines. These machines, along with the measurement of biochemical markers by the hospital laboratory, facilitate the care of patients with severe conditions who present to the ED. However, discrepancies have been noted between the Arterial Blood Gas (ABG) analyzers in the ED and the hospital laboratory autoanalyzer in relation to electrolyte and hemoglobin measurements. The present study was performed to determine whether the ABG and laboratory measurements of potassium, sodium, and hemoglobin levels are equivalent, and whether ABG analyzer results can be used to guide clinical care before the laboratory results become available.Materials and MethodsStudy power analyses revealed that 200 consecutive patients who presented to our ED would allow this prospective single-center cohort study to detect significant differences between ABG- and laboratory-measured potassium, sodium, and hemoglobin levels. Paired arterial and venous blood samples were collected within 30 minutes. Arterial blood samples were measured in the ED by an ABL 90 FLEX blood gas analyzer. The biochemistry and blood cell counts of the venous samples were measured in the hospital laboratory. The potassium, sodium, and hemoglobin concentrations obtained by both methods were compared by using paired Student’s t-test, Spearman’s correlation, Bland-Altman plots, and Deming regression.ResultsThe mean ABG and laboratory potassium values were 3.77±0.44 and 4.2±0.55, respectively (P<0.0001). The mean ABG and laboratory sodium values were 137.89±5.44 and 140.93±5.50, respectively (P<0.0001). The mean ABG and laboratory Hemoglobin values were 12.28±2.62 and 12.35±2.60, respectively (P = 0.24).ConclusionAlthough there are the statistical difference and acceptable biases between ABG- and laboratory-measured potassium and sodium, the biases do not exceed USCLIA-determined limits. In parallel, there are no statistical differences and biases beyond USCLIA-determined limits between ABG- and laboratory-measured hemoglobin. Therefore, all three variables measured by ABG were reliable.

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Section: Discussionmentioning

confidence: 99%

Analysis of Bias in Measurements of Potassium, Sodium and Hemoglobin by an Emergency Department-Based Blood Gas Analyzer Relative to Hospital Laboratory Autoanalyzer Results

Zhang

Zhao

2015

PLoS ONE

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“…19 A study reported by Arthurs et al that aimed to compare the traditional blood measurement system with POC measurements using a blood gas analyser indicated a very good agreement between measurements, with a further advantage that multiple assays of POCT can be completed with smaller blood volume units compared with traditional laboratory assays, minimising sample handling and reducing unnecessary trauma to babies. 20 Moreover, the introduction of the POC analyser led to significant financial savings as the overall laboratory costs were reduced by £39,000 (−24.5%) per annum. 20 The cost-effectiveness of the multi-parameter Point-of-Care-blood test analyses was also confirmed by others.…”

Section: Point-of-care Testing Related To Maternal and Neonatal Carementioning

confidence: 99%

“…20 Moreover, the introduction of the POC analyser led to significant financial savings as the overall laboratory costs were reduced by £39,000 (−24.5%) per annum. 20 The cost-effectiveness of the multi-parameter Point-of-Care-blood test analyses was also confirmed by others. [21][22][23] As already mentioned above, there are several factors explaining why women living in rural/remote communities are more vulnerable to pregnancy-related complications than women living in urban areas.…”

Section: Point-of-care Testing Related To Maternal and Neonatal Carementioning

confidence: 99%

<p>Review of Health Economics of Point-of-Care Testing Worldwide and Its Efficacy of Implementation in the Primary Health Care Setting in Remote Australia</p>

Wong

Marcu

Bezak

et al. 2020

RMHP

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There are important differences concerning health outcomes between the Australian population living in rural/remote regions and the urban population. Health care provision in remote areas, particularly in regions with a low number of inhabitants, is not without challenges. Aboriginal, rural and remote communities are therefore affected, as they face various obstacles in accessing health services, owing to geographical settings, difficulties in transportation to nearby hospitals, limited or inexistent local qualified personnel. The implementation of point-of-care testing could be a plausible solution to these challenges, as various point-of-care services that have been successfully put into action worldwide indicate towards positive clinical outcomes. Point-of-care units have a real potential in reducing morbidity and mortality in all population groups. This article aims to review the published literature on point-of-care testing around the world, with a focus on health economics and the feasibility of its implementation in Australian rural and remote regions.

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A Comparative Study on Reliability of Point of Care Sodium and Potassium Estimation in a Pediatric Intensive Care Unit

et al. 2013

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Clinical Impact of Point-of-Care Testing Using the OMNI-S Blood Gas Analyzer in a Neonatal Intensive Care Setting

Cited by 3 publications

References 19 publications

Analysis of Bias in Measurements of Potassium, Sodium and Hemoglobin by an Emergency Department-Based Blood Gas Analyzer Relative to Hospital Laboratory Autoanalyzer Results

Analysis of Bias in Measurements of Potassium, Sodium and Hemoglobin by an Emergency Department-Based Blood Gas Analyzer Relative to Hospital Laboratory Autoanalyzer Results

<p>Review of Health Economics of Point-of-Care Testing Worldwide and Its Efficacy of Implementation in the Primary Health Care Setting in Remote Australia</p>

A Comparative Study on Reliability of Point of Care Sodium and Potassium Estimation in a Pediatric Intensive Care Unit

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