Clinical implications of innate immune exhaustion in cystic fibrosis
Rikke Møller,
Bibi Uhre Nielsen,
Elio Rossi
et al.
Abstract:ObjectivesThe lung disease progression in people with cystic fibrosis (pwCF) varies from one individual to another. Different immunological characteristics have been suggested to explain this variation, and we hypothesized that lung capacity may be associated with the innate immune response in pwCF. In an exploratory study, we aimed to investigate potential links between the innate immune response and lung function in pwCF using the standardized immune function assay TruCulture.MethodsIn a single-centre study … Show more
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