Clinical Implications of Oscillatory Lung Function during Methacholine Bronchoprovocation Testing of Preschool Children

Choi, Sun Hee; Sheen, Youn Ho; Kim, Mi Ae; Baek, Ji Hyeon; Baek, Hey Sung; Lee, Seung Jin; Yoon, Jung Won; Rha, Yeong Ho; Han, Man Yong

doi:10.1155/2017/9460190

Cited by 5 publications

(4 citation statements)

References 30 publications

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“…Such cut-offs could have better clinical utility than spirometry-based tests. Airway hyperresponsiveness measured by oscillometry is reproducible [28,30,41,143] and is correlated with responsiveness measured by forced expiratory volume in 1 s (FEV 1 ).…”

Section: Bronchial Challenge Testingmentioning

confidence: 94%

Technical standards for respiratory oscillometry

King

Bates

Berger³

et al. 2019

Eur Respir J

419

496

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Oscillometry (also known as the forced oscillation technique) measures the mechanical properties of the respiratory system (upper and intrathoracic airways, lung tissue and chest wall) during quiet tidal breathing, by the application of an oscillating pressure signal (input or forcing signal), most commonly at the mouth. With increased clinical and research use, it is critical that all technical details of the hardware design, signal processing and analyses, and testing protocols are transparent and clearly reported to allow standardisation, comparison and replication of clinical and research studies. Because of this need, an update of the 2003 European Respiratory Society (ERS) technical standards document was produced by an ERS task force of experts who are active in clinical oscillometry research.The aim of the task force was to provide technical recommendations regarding oscillometry measurement including hardware, software, testing protocols and quality control.The main changes in this update, compared with the 2003 ERS task force document are 1) new quality control procedures which reflect use of “within-breath” analysis, and methods of handling artefacts; 2) recommendation to disclose signal processing, quality control, artefact handling and breathing protocols (e.g. number and duration of acquisitions) in reports and publications to allow comparability and replication between devices and laboratories; 3) a summary review of new data to support threshold values for bronchodilator and bronchial challenge tests; and 4) updated list of predicted impedance values in adults and children.

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Section: Bronchial Challenge Testingmentioning

confidence: 94%

Technical standards for respiratory oscillometry

King

Bates

Berger³

et al. 2019

Eur Respir J

419

496

View full text Add to dashboard Cite

show abstract

“…AHR detected by oscillometry is repeatable [47,49,61,72] and correlates with responsiveness based on FEV 1 [73], but the correlations of spirometry and oscillometry are inconsistent. There is wide variability across studies, which may be explained by differences in methodology and study populations.…”

Section: Bronchial Challenge Testingmentioning

confidence: 99%

Clinical significance and applications of oscillometry

Kaminsky

Simpson

Berger³

et al. 2022

Eur Respir Rev

105

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Recently, “Technical standards for respiratory oscillometry” was published, which reviewed the physiological basis of oscillometric measures and detailed the technical factors related to equipment and test performance, quality assurance and reporting of results. Here we present a review of the clinical significance and applications of oscillometry. We briefly review the physiological principles of oscillometry and the basics of oscillometry interpretation, and then describe what is currently known about oscillometry in its role as a sensitive measure of airway resistance, bronchodilator responsiveness and bronchial challenge testing, and response to medical therapy, particularly in asthma and COPD. The technique may have unique advantages in situations where spirometry and other lung function tests are not suitable, such as in infants, neuromuscular disease, sleep apnoea and critical care. Other potential applications include detection of bronchiolitis obliterans, vocal cord dysfunction and the effects of environmental exposures. However, despite great promise as a useful clinical tool, we identify a number of areas in which more evidence of clinical utility is needed before oscillometry becomes routinely used for diagnosing or monitoring respiratory disease.

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“…Bronchial hyper-responsiveness studies comparing FOT with different lung function measures have reported FOT to be as effective as spirometry[ 63 - 69 ] and as sensitive as body plethysmography[ 70 ] and transcutaneous PO 2 [ 50 ] in older children with asthma. BHR has been assessed using FOT in children younger than 7 years of age with a range of challenge tests including adenosine monophosphate (AMP)[ 19 ], cold air[ 24 ], normal saline[ 21 ] methacholine[ 22 , 62 , 63 , 66 , 68 , 71 ], mannitol[ 25 ] and exercise[ 20 , 72 ] demonstrating that FOT can be reliably used in young children for challenge testing.…”

Section: Introductionmentioning

confidence: 99%

Is forced oscillation technique the next respiratory function test of choice in childhood asthma

Alblooshi¹,

Alkalbani²,

Albadi³

et al. 2017

WJM

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Respiratory diseases, especially asthma, are common in children. While spirometry contributes to asthma diagnosis and management in older children, it has a limited role in younger children whom are often unable to perform forced expiratory manoeuvre. The development of novel diagnostic methods which require minimal effort, such as forced oscillation technique (FOT) is, therefore, a welcome and promising addition. FOT involves applying external, small amplitude oscillations to the respiratory system during tidal breathing. Therefore, it requires minimal effort and cooperation. The FOT has the potential to facilitate asthma diagnosis and management in pre-school children by faciliting the objective measurement of baseline lung function and airway reactivity in children unable to successfully perform spirometry. Traditionally the use of FOT was limited to specialised centres. However, the availability of commercial equipment resulted in its use both in research and in clinical practice. In this article, we review the available literature on the use of FOT in childhood asthma. The technical aspects of FOT are described followed by a discussion of its practical aspects in the clinical field including the measurement of baseline lung function and associated reference ranges, bronchodilator responsiveness and bronchial hyper-responsiveness. We also highlight the difficulties and limitations that might be encountered and future research directions.

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Clinical Implications of Oscillatory Lung Function during Methacholine Bronchoprovocation Testing of Preschool Children

Cited by 5 publications

References 30 publications

Technical standards for respiratory oscillometry

Technical standards for respiratory oscillometry

Clinical significance and applications of oscillometry

Is forced oscillation technique the next respiratory function test of choice in childhood asthma

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