“…A total of 16 studies involving 1,488 patients ( 8 , 10 , 12 – 14 , 16 – 21 , 23 – 27 ) were pooled for an assessment of functional outcome, in which 13 studies involving 1,347 patients had this reported at 90 days ( 10 , 12 , 13 , 16 – 21 , 23 , 25 – 27 ). Four studies ( n = 324) ( 10 , 12 , 19 , 20 ) were performed on recanalization therapy, three ( 10 , 19 , 20 ) of which were intravenous thrombolysis (IVT), and one ( 12 ) of which combined endovascular treatment (EVT) with IVT. Five studies ( n = 951) reported END ( 9 , 11 , 13 , 15 , 22 ), while six studies ( n = 352) reported the risk of HT ( 8 , 10 , 20 , 24 , 26 ).…”