Clinical implications of the P wave duration and dispersion: Relationship between atrial conduction defects and abnormally prolonged and fractionated atrial endocardial electrograms

Centurión, Osmar Antonio

doi:10.1016/j.ijcard.2008.12.072

Cited by 41 publications

(41 citation statements)

References 24 publications

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“…Coronary artery disease, hypertension, obesity, and valvular heart disease have an impact on P d values (12). A predictive role of P d for prolonged interatrial and intra-atrial conduction times has been demonstrated in a previous study (13). In addition, elevated Pd values have been presented to be related to a raised risk of paroxysmal atrial fibrillation (11).…”

Section: Introductionmentioning

confidence: 86%

P-Wave and QT Dispersion in Pregnant Women with Preeclampsia

Çakmak¹,

Çakmak²,

Özgen³

et al. 2016

JAREM

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Objective: Preeclampsia is an important cause of maternal and fetal mortality and morbidity worldwide. P-wave dispersion (P d ) and QT interval dispersion (QT d ) are direct measures of the nonhomogenity of atrial depolarization and ventricular repolarization, respectively, in electrocardiography (ECG). Recent studies have reported a significant role of prolonged P d and QT d in various cardiovascular diseases. Because the effect of acute pressure overload, which occurs in a preeclamptic setting, on the intra-and/or interatrial and ventricular conduction times remains unknown, we aimed to investigate the relation of P d and QT d with the presence and severity of preeclampsia.Methods: Forty-eight consecutive pregnant women with preeclampsia and 55 healthy, age-matched pregnant women were included in this retrospective study between January and September 2015. The pregnant women with preeclampsia were divided into two groups according to disease severity as follows: mild and severe preeclampsia. A 12-lead ECG was performed for all the pregnant women before cesarean section operation.Results: Compared with the healthy pregnant women, P d and QT d were significantly prolonged in patients with preeclampsia. Moreover, in the subgroups of preeclampsia, P d was significantly increased in the severe group. P d and QT d were directly related to systolic and diastolic blood pressure, which are well-known validated indicators for the severity of preeclampsia. Conclusion:Preeclampsia triggers an alteration of atrial depolarization and ventricular repolarization, which are evidenced by the prolongation of ECG parameters such as P d and QT d . ECG is a noninvasive, easy to use, and easily available diagnostic tool, which can be used in the assessment of atrial and ventricular electrical activity in pregnant women with preeclampsia.

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Section: Introductionmentioning

confidence: 86%

P-Wave and QT Dispersion in Pregnant Women with Preeclampsia

Çakmak¹,

Çakmak²,

Özgen³

et al. 2016

JAREM

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“…Ohe et al [1] defined FAA elicited by atrial extra stimuli as the occurrence of disorganized atrial activity >150% of the duration of the local atrial electrogram of the basic beat recorded in the right atrium. The duration of the local atrial electrogram and the induction zone of FAA are greater in patients with PAF than in controls [1,2]. Although FAA also is elicited in subjects without paroxysmal AF, the widening of FAA zone is characteristic of paroxysmal AF.…”

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confidence: 89%

“…It has been demonstrated that fragmentation and slowing of conduction in response to premature stimulation are related to paroxysmal AF [1,2,13]. Fractionated auricular electrograms are recorded from myocardial sites where auricular muscle fibers are widely separated by fibrosis that has resulted from ischemia, inflammation, or degeneration [14].…”

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confidence: 99%

Atrial Electrophysiological Modifications Generated by a Single Atrial Premature Contraction

Centurión¹

2015

JCCR

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“…The normal value of PWD was found to be 29 ± 9 ms, and values greater than 40 ms indicate the presence of heterogeneous electrical activity in different regions of the atrium that might cause AF to develop [13]. It has been shown that increased P-wave duration and PWD reflect prolongation of intra-atrial and interatrial conduction time and the inhomogeneous atrial propagation of sinus impulses [12][13][14].…”

mentioning

confidence: 96%

“…The P wave of the electrocardiogram may show alterations that can be associated with atrial arrhythmias and AF. P-wave dispersion (PWD) is considered a noninvasive electrocardiographic (ECG) marker for atrial remodeling and predictor for AF [12][13][14][15]. PWD reflects disturbances of intra-atrial and inter-atrial conduction, and it is defined as the difference between the wider and the narrower P-wave duration recorded from the 12 ECG leads at a paper speed of 50 mm/s.…”

mentioning

confidence: 99%

P Wave Duration and Dispersion as a Useful Conventional Electrocardiographic Marker for Atrial Fibrillation Prediction

2017

JCCR

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Clinical implications of the P wave duration and dispersion: Relationship between atrial conduction defects and abnormally prolonged and fractionated atrial endocardial electrograms

Cited by 41 publications

References 24 publications

P-Wave and QT Dispersion in Pregnant Women with Preeclampsia

P-Wave and QT Dispersion in Pregnant Women with Preeclampsia

Atrial Electrophysiological Modifications Generated by a Single Atrial Premature Contraction

P Wave Duration and Dispersion as a Useful Conventional Electrocardiographic Marker for Atrial Fibrillation Prediction

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