Clinical Indications for Cardiovascular Magnetic Resonance (CMR): Consensus Panel Report #

Pennell, Dudley J.; Sechtem, Udo; Higgins, Charles B.; Manning, Warren J.; Pohost, Gerald M.; Rademakers, Frank; Rossum, Albert C. van; Shaw, Leslee J.; Yucel, Evin

doi:10.1081/jcmr-200038581

Cited by 290 publications

(234 citation statements)

References 387 publications

(374 reference statements)

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“…CMR is a relatively new tool for the assessment of myocardial perfusion, but its place in the detection of myocardial ischemia and CFR is well established [5]. Studies [6,12,13] show that the sensitivity of CMR in myocardial perfusion assessment is similar to the positron emission tomography, which is considered to be a gold standard for perfusion investigations.…”

Section: Discussionmentioning

confidence: 99%

“…However, the use of this technique is limited by its reduced availability. CMR is widely used for assessment of myocardial perfusion in patients with obstructive coronary heart disease [5,14]. But its utility has been shown also in patients with chest pain and no obstructive coronary artery disease in coronary angiography [7].…”

Section: Discussionmentioning

confidence: 99%

“…Cardiovascular magnetic resonance (CMR) offers the possibility to study noninvasively myocardial perfusion [5,6]. Recently, several interesting CMR studies [7][8][9] examined the myocardial blood flow and flow reserve in patients with cardiac X syndrome.…”

Section: Introductionmentioning

confidence: 99%

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Myocardial perfusion in hypertensive patients with normal coronary angiograms

Kawecka‐Jaszcz¹,

Czarnecka²,

Olszanecka³

et al. 2008

Journal of Hypertension

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Myocardial perfusion in hypertensive patients with normal coronary angiograms

Kawecka‐Jaszcz¹,

Czarnecka²,

Olszanecka³

et al. 2008

Journal of Hypertension

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“…In the present study THV was determined by CMR, which is considered the gold standard for assessing cardiac dimensions and function [13]. In situations when CMR is not available or is contraindicated, i.e.…”

Section: Discussionmentioning

confidence: 99%

Peak oxygen uptake in relation to total heart volume discriminates heart failure patients from healthy volunteers and athletes

Engblom

Steding

Carlsson

et al. 2010

Journal of Cardiovascular Magnetic Resonance

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BackgroundAn early sign of heart failure (HF) is a decreased cardiac reserve or inability to adequately increase cardiac output during exercise. Under normal circumstances maximal cardiac output is closely related to peak oxygen uptake (VO2peak) which has previously been shown to be closely related to total heart volume (THV). Thus, the aim of this study was to derive a VO2peak/THV ratio and to test the hypothesis that this ratio can be used to distinguish patients with HF from healthy volunteers and endurance athletes. Thirty-one patients with HF of different etiologies were retrospectively included and 131 control subjects (60 healthy volunteers and 71 athletes) were prospectively enrolled. Peak oxygen uptake was determined by maximal exercise test and THV was determined by cardiovascular magnetic resonance. The VO2peak/THV ratio was then derived and tested.ResultsPeak oxygen uptake was strongly correlated to THV (r2 = 0.74, p < 0.001) in the control subjects, but not for the patients (r2 = 0.0002, p = 0.95). The VO2peak/THV ratio differed significantly between control subjects and patients, even in patients with normal ejection fraction and after normalizing for hemoglobin levels (p < 0.001). In a multivariate analysis the VO2peak/THV ratio was the only independent predictor of presence of HF (p < 0.001).ConclusionsThe VO2peak/THV ratio can be used to distinguish patients with clinically diagnosed HF from healthy volunteers and athletes, even in patients with preserved systolic left ventricular function and after normalizing for hemoglobin levels.

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“…Therefore, the assessment and regular monitoring of right ventricular function is of utmost importance. Cardiac magnetic resonance imaging (cardiac MRI) is considered to be the gold standard in the morphologic and functional evaluation of the heart [10,11,12,13,14]. In this review, we primarily focus on the evolving role of MRI in the management of PH.…”

Section: General Management Of Patients With Pulmonary Hypertensionmentioning

confidence: 99%

The Emerging Role of Magnetic Resonance Imaging in the Diagnosis and Management of Pulmonary Hypertension

Kovàcs

Reiter

et al. 2008

Respiration

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Pulmonary hypertension is a life-threatening chronic disorder of the pulmonary circulation. Elevated pressure and resistance in the pulmonary vessels lead to progressive right heart failure which results in functional limitations and ultimately the death of most patients. Thus, the monitoring of right ventricular (RV) function is of great importance. Cardiac magnetic resonance imaging (cardiac MRI) has several advantages over other imaging methods. The use of cine acquisition techniques allows precise description of characteristic volumetric and functional variables, such as right ventricular volumes, muscle mass, stroke volume, ejection fraction, or cardiac output. Impaired right ventricular contractility and function have also been assessed using measures like ventricular septal bowing and pressure-volume loops. MRI investigations have been performed to monitor medical treatment, and the improvement in well-established prognostic factors, such as the 6-min walk, were correlated with measures of right ventricular function. Flow-derived parameters of the pulmonary arteries (such as peak velocity, acceleration time and volume, or pulmonary flow profile) are available using velocity-encoded imaging, and may detect early signs of remodelling. Additionally, magnetic resonance angiography is a promising new tool to visualise pulmonary perfusion and to diagnose chronic thromboembolic pulmonary hypertension. The purpose of this review is to summarise recent advances of cardiovascular magnetic resonance imaging, which will play an increasing role in the comprehensive diagnostic work-up of patients with pulmonary hypertension as a tool to monitor the course of the disease and to evaluate new therapeutic approaches.

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Clinical Indications for Cardiovascular Magnetic Resonance (CMR): Consensus Panel Report #

Cited by 290 publications

References 387 publications

Myocardial perfusion in hypertensive patients with normal coronary angiograms

Myocardial perfusion in hypertensive patients with normal coronary angiograms

Peak oxygen uptake in relation to total heart volume discriminates heart failure patients from healthy volunteers and athletes

The Emerging Role of Magnetic Resonance Imaging in the Diagnosis and Management of Pulmonary Hypertension

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