“…1 In the absence of any criterion or diagnostic gold standards it has been suggested that pain states characterized by a dominance of 'nociceptive', 'peripheral neuropathic' and 'central' mechanisms may be distinguishable from one another clinically, based on the pattern recognition of clusters of symptoms and signs particular to each category. 2,10 Employing a methodology considered suitable for classification system development, 11,12 an expert consensus-derived list of clinical criteria associated with such mechanistic classifications has recently been generated; 13 however, the reliability of clinical judgments and criteria associated with mechanismsbased classifications of pain has not been previously tested. Classification system validation is a multistep process, 14 and proof of reliability is considered a prerequisite of validity, 15 i.e.…”