Clinical interpretation of the Uremic Pruritus in Dialysis Patients (<scp>UP</scp>‐Dial) scale: a novel instrument for the assessment of uremic pruritus

Nochaiwong, Surapon; Ruengorn, Chidchanok; Koyratkoson, Kiatkriangkrai; Chaisai, Chayutthaphong; Awiphan, Ratanaporn; Thavorn, Kednapa; Noppakun, Kajohnsak; Suteeka, Yuttitham; Panyathong, Setthapon; Chongruksut, Wilaiwan; Nanta, Sirisak; Chiewchanvit, Siri

doi:10.1111/jdv.14609

Cited by 9 publications

(7 citation statements)

References 38 publications

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“…The set U of the possible banding was preferred as the optimal 10-item COVID-PSS cut-off scores based on the κ coefficient (online supplemental table S9) and AuROC (online supplemental table S10). The categorised scores were proposed as no/minimal (≤18), moderate (19)(20)(21)(22)(23)(24)(25) and high (≥26), reflecting public values and perspectives on the anchor-based questions. The AuROC demonstrated the following ranges: no/minimal (0.65-0.82), moderate (0.50-0.65) and high (0.75-0.80).…”

Section: Resultsmentioning

confidence: 99%

COVID-19 Public Stigma Scale (COVID-PSS): development, validation, psychometric analysis and interpretation

et al. 2021

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ObjectiveAmid the COVID-19 pandemic, social stigma towards COVID-19 infection has become a major component of public discourse and social phenomena. As such, we aimed to develop and validate the COVID-19 Public Stigma Scale (COVID-PSS).Design and settingNational-based survey cross-sectional study during the lockdown in Thailand.ParticipantsWe invited the 4004 adult public to complete a set of measurement tools, including the COVID-PSS, global fear of COVID-19, perceived risk of COVID-19 infection, Bogardus Social Distance Scale, Pain Intensity Scale and Insomnia Severity Index.MethodsFactor structure dimensionality was constructed and reaffirmed with model fit by exploratory and confirmatory factor analyses and non-parametric item response theory (IRT) analysis. Psychometric properties for validity and reliability were tested. An anchor-based approach was performed for classifying the proper cut-off scores.ResultsAfter factor analysis, IRT analysis and test for model fit, we created the final 10-item COVID-PSS with a three-factor structure: stereotype, prejudice and fear. Face and content validity were established through the public and experts’ perspectives. The COVID-PSS was significantly correlated (Spearman rank, 95% CI) with the global fear of COVID-19 (0.68, 95% CI 0.66 to 0.70), perceived risk of COVID-19 infection (0.79, 95% CI 0.77 to 0.80) and the Bogardus Social Distance Scale (0.50, 95% CI 0.48 to 0.53), indicating good convergent validity. The correlation statistics between the COVID-PSS and the Pain Intensity Scale and Insomnia Severity Index were <0.2, supporting the discriminant validity. The reliability of the COVID-PSS was satisfactory, with good internal consistency (Cronbach’s α of 0.85, 95% CI 0.84 to 0.86) and test–retest reproducibility (intraclass correlation of 0.94, 95% CI 0.86 to 0.96). The proposed cut-off scores were as follows: no/minimal (≤18), moderate (19–25) and high (≥26) public stigma towards COVID-19 infection.ConclusionsThe COVID-PSS is practical and suitable for measuring stigma towards COVID-19 in a public health survey. However, cross-cultural adaptation may be needed.

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Section: Resultsmentioning

confidence: 99%

COVID-19 Public Stigma Scale (COVID-PSS): development, validation, psychometric analysis and interpretation

et al. 2021

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“…This inconsistency implies that a simple VAS may not be sufficient for predicting the overall effects of pruritus severity on outcomes. The Thai Renal Outcome Research group published a multidimensional assessment tool for UP, which included symptoms, signs, effects on sleep, and daily activities in 2017 [ 52 ]. This questionnaire may be adapted for future studies on UP.…”

Section: Discussionmentioning

confidence: 99%

Uremic pruritus and long-term morbidities in the dialysis population

et al. 2020

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Background Uremic pruritus (UP) is a multifactorial problem that contributes to low quality of life in dialysis patients. The long-term influences of UP on dialysis patients are still poorly understood. This study aims to elucidate the contribution of UP to long-term outcomes. Materials and method We used the Taiwan National Health Insurance Research Database to conduct this study. Patients on chronic dialysis were included and divided into UP and non-UP groups according to the long-term prescription of antihistamine in the absence of other indications. The outcomes include infection-related hospitalization, catheter-related infection, major adverse cardiac and cerebrovascular events (MACCE) and parathyroidectomy. Results After propensity score matching, 14,760 patients with UP and 29,520 patients without UP were eligible for analysis. After a mean follow-up of 5 years, we found that infection-related hospitalization, MACCE, catheter-related infection, heart failure and parathyroidectomy were all slightly higher in the UP than non-UP group (hazard ratio: 1.18 [1.16–1.21], 1.05 [1.01–1.09], 1.16 [1.12–1.21], 1.08 [1.01–1.16] and 1.10 [1.01–1.20], respectively). Subgroup analysis revealed that the increased risk of adverse events by UP was generally more apparent in younger patients and patients who underwent peritoneal dialysis. Conclusion UP may be significantly associated with an increased risk of long-term morbidities.

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“…The total score of UP-Dial also enables classifying the severity of itch. Moreover, Nochaiwong et al [ 22 ] proposed cut-off points of this instrument, which present as follows: ≤ 12 points indicate mild, 13-21 points moderate and ≥ 22 points severe itch.…”

Section: Discussionmentioning

confidence: 99%

Uraemic Pruritus in Dialysis Patient (UP-Dial) questionnaire: creation and validation of the Polish language version

Świerczyńska-Mróz¹,

Krajewski²,

Reszke³

et al. 2022

pdia

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Introduction Uraemic pruritus is a common and burdensome symptom in patients undergoing haemodialysis. Though a significant negative impact of chronic itch on patient’s quality of life is proved, this problem is still often underestimated in clinical practice. Various instruments describing itch are in use, however only recently a specific instrument for uraemic itch – Uraemic Pruritus in Dialysis Patient (UP-Dial) – questionnaire has been created. Aim To translate and to validate the Polish version of the UP-Dial questionnaire. Material and methods Forward and backward translations were conducted according to international standards. The validation was performed on a group of 30 patients undergoing haemodialysis and suffering from uraemic itch. Respondents completed the questionnaire twice with a 3–7 days’ interval. Moreover, for convergent validity, the subjects were asked to assess their itch with the Numerical Rating Scale (NRS), 4-Item Itch Questionnaire (4IIQ) as well as ItchyQoL questionnaire. Results The Polish version of the UP-Dial questionnaire showed very good internal consistency – Cronbach α coefficient was 0.90 for total score. The reproducibility assessed with the intraclass correlation coefficient (ICC) was also very good – 0.9. Furthermore, UP-Dial correlated strongly with NRS ( r = 0.74, p < 0.01), 4IIQ ( r = 0.82, p < 0.01) and ItchyQoL ( r = 0.88, p < 0.01). Conclusions The Polish version of the UP-Dial questionnaire showed high internal reliability, validity and reproducibility and can be widely used both in research and in daily clinical practice.

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Clinical interpretation of the Uremic Pruritus in Dialysis Patients (UP‐Dial) scale: a novel instrument for the assessment of uremic pruritus

Abstract: The estimated UP-Dial severity band can facilitate the interpretation of UP in practice-based research settings and can be used to support treatment decisions.

Cited by 9 publications

References 38 publications

COVID-19 Public Stigma Scale (COVID-PSS): development, validation, psychometric analysis and interpretation

COVID-19 Public Stigma Scale (COVID-PSS): development, validation, psychometric analysis and interpretation

Uremic pruritus and long-term morbidities in the dialysis population

Uraemic Pruritus in Dialysis Patient (UP-Dial) questionnaire: creation and validation of the Polish language version

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