Clinical Investigation of Benign Asbestos Pleural Effusion

Fujimoto, Nobukazu; Gemba, Kenichi; Aoe, Keisuke; Kato, Katsuya; Yokoyama, Takako; Usami, Ikuji; Onishi, Kazuo; Mizuhashi, Keiichi; Yusa, Toshikazu; Kishimoto, Takumi

doi:10.1155/2015/416179

Cited by 24 publications

(26 citation statements)

References 23 publications

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“…Occupational and/or environmental exposure to some types of asbestos fibers is related with both malignant and nonmalignant pulmonary diseases (1)(2)(3), of which malignant mesothelioma (MM) and lung cancer are the most typical ones (4). Instead, non-malignant asbestos-related diseases include pleural plaques (PPs), pleural effusions, diffuse pleural thickening and parenchymal fibrosis (5)(6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%

Immunomodulatory effects in workers exposed to naturally occurring asbestos fibers

Ledda

Costa

Matera

et al. 2017

Molecular Medicine Reports

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Natural asbestiform fibers are defined 'naturally occurring asbestos' (NOA) and refer to the mineral as a natural component of soils or rocks. The release of NOA fibers into the air from rocks or soils by routine human activities or natural weathering processes represents a risk for human beings. Fluoro-edenite (FE) is a NOA fiber detected in the benmoreitic lava in the area of Biancavilla, South-west slope of Mt. Etna. The aim of the present study was to investigate FE immunotoxicity pathways in a group of 38 occupationally exposed construction workers, in order to find any biological markers of its effect. Subjects underwent respiratory function tests and HRCT total chest scanning. Serum IL-1β, IL-6, IL-8 and TNF-α were measured. The presence of PPs was significantly greater in subjects exposed than in the control (25 vs. 2). In subjects exposed to FE, IL-1β and TNF-α values were significantly higher than the controls. The previously observed increase of IL-1β and IL-18 showed a probable involvement of the proteic complex defined inflammosome by FE fibers.

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Section: Introductionmentioning

confidence: 99%

Immunomodulatory effects in workers exposed to naturally occurring asbestos fibers

Ledda

Costa

Matera

et al. 2017

Molecular Medicine Reports

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“…Asbestos-related changes of pleura include also benign asbestos pleural effusion, which is a nonmalignant pleural disease [39]. It has been first described in 1964, and it is also known as asbestos pleurisy [39,40].…”

Section: Pleural Effusionmentioning

confidence: 99%

“…Diagnostic criteria for asbestos pleural effusion include previous asbestos exposure, determination of pleural effusion by chest radiograph, HRCT or thoracocentesis, and the absence of other causes of effusion [39]. In the vast majority of undiagnosed unilateral pleural effusions, the fluid is sent for cytological analysis.…”

Section: Pleural Effusionmentioning

confidence: 99%

Asbestos-Related Pleural Diseases: The Role of Gene-Environment Interactions

Dolžan¹,

Franko²

2020

Diseases of Pleura

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Several pleural diseases have been associated with asbestos exposure. Asbestos exposure may lead to the development of benign pleural diseases, such as pleural plaques, diffuse pleural thickening, and pleural effusion, as well as to the development of malignant mesothelioma, a highly aggressive tumour of the pleura. Asbestos exposure related to pleural diseases may be occupational or environmental. Although the causal relationship between asbestos-related pleural diseases and asbestos exposure has been well confirmed, the role of genetic factors in the development of these diseases needs to be further investigated and elucidated. The results of the studies performed so far indicate that in addition to asbestos exposure, genetic factors as well as the interactions between genetic factors and asbestos exposure may have an important impact on the risk of asbestos-related pleural diseases, especially malignant mesothelioma. This chapter aims to present how the risk of developing asbestos-related pleural diseases may be influenced by asbestos exposure, genetic factors, interactions between different genetic factors, as well as interactions between different genetic factors and asbestos exposure.

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“…Einkenni geta verið brjóstverkir og maeði en þegar asbestútsettu fólki hefur verið fylgt eftir með röntgenmyndum hefur fundist að allt að tveir þriðju einstaklinga eru einkennalausir. 31 Fleiðruvökvinn getur verið einn sér eða með fleiðruskellum, dreifðum fleiðruþykknunum og kölkunum í fleiðru. Mynd 2 sýnir fleiðruvökva.…”

Section: Góðkynja Fleiðruvökvi (Benign Pleural Effusion)unclassified

Asbest og áhrif þess á heilsufar Íslendinga

Guðmundsson

Tómasson

2019

LBL

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Hvað er asbest Orðið asbest kemur úr grísku og merkir það sem ekki eyðist. Asbest er samheiti yfir nokkrar steintegundir sem allar eiga það sameiginlegt að mynda þráðkennda kristalla. 1 Þannig er um að raeða þráðlaga kristölluð sílikat-steinefni sem hafa mismunandi byggingu og eiginleika. Þau algengustu eru krýsótíl (hvítt asbest), sem er um 90% af asbestframleiðslu heimsins, krókídólít (blátt asbest), amósít (brúnt asbest), antófyllít, tremólít og aktínólít. 2 Asbest er unnið úr námum á svaeðum þar sem mikið finnst af því og það er flutt til frekari vinnslu í verksmiðjur þar sem það er molað niður og þraeðirnir aðskildir. 1,2 Asbest sem steinefni finnst í mjög litlu magni í náttúru Íslands. Kristallabygging asbests gerir það að verkum að haegt er að kljúfa það að endilöngu en þraeðirnir eru mun sterkari á lengdina og er það eitt af einkennum á asbestþraeði. Ef asbestögn á að teljast þráður verður lengdin að vera að minnsta kosti þrisvar sinnum meiri en breiddin. 1,2 Asbestþraeðir eru mjög slitsterkir og þola mjög mikinn hita. Það var því algengt að asbest vaeri notað sem brunavarnarefni, hitaeinangrun og við ýmiss konar iðnað þar sem mikill hiti er notaður. Asbest er enn notað í miklu magni í heiminum, ekki síst í þróunarríkjunum. 1 Þar eru í notkun eldri innfluttar vélar frá Vesturlöndum sem framleiða asbestafurðir. Þann 1. janúar 2005 gekk í gildi allsherjarbann við notkun asbests á Evrópska efnahagssvaeðinu. Í dag er því bannað að flytja inn, framleiða eða nota asbest á Íslandi. Við vinnu með asbest þyrlast upp nálar-eða þráðlaga asbestryk. 2 Það er þetta ryk sem er haettulegt heilsunni. Margar rykagnirnar eru mjög smáar og léttar og geta svifið um í marga daga. Staerð og lögun þráðanna hafa áhrif á hversu vel þeim gengur að komast inn í líkamann. 2

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Clinical Investigation of Benign Asbestos Pleural Effusion

Cited by 24 publications

References 23 publications

Immunomodulatory effects in workers exposed to naturally occurring asbestos fibers

Immunomodulatory effects in workers exposed to naturally occurring asbestos fibers

Asbestos-Related Pleural Diseases: The Role of Gene-Environment Interactions

Asbest og áhrif þess á heilsufar Íslendinga

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