Professional psychologists sometimes make more pathological judgments for clients with socially deviant faith (high religiousness or spirituality) than for otherwise identical clients with socially normative faith (low religiousness or spirituality). This phenomenon is called clinical judgment faith bias, and this study used mathematical modeling to investigate whether this occurs in psychological practice. Previously, Harris (2011) surveyed a national random sample of 141 psychologists in clinical practice to investigate clinical judgment faith bias with a specially designed clinical vignette. The current study reanalyzed the data from Harris (2011), testing 2 alternative regression models with multivariate multiple regressions. The test of the first model was not significant; neither the faith magnitude of a vignette (ranging from low to high) nor its faith type (religious or spiritual) influenced the diagnostic or prognostic judgments of most psychologists. The analysis of the second model yielded significant results-but, unexpectedly, an inverse clinical judgment faith bias was found for the prognostic judgments of highly spiritual psychologists. The more spiritual (but not religious) psychologists were, the more they responded to socially deviant cases by making more positive prognostic judgments. Furthermore, a multicultural knowledge prognostic bias was found-the more multicultural knowledge (but not awareness) psychologists had, the more positive prognostic judgments they made for all cases. These findings are unexpected, contradict predictions, and must be interpreted with caution but suggest prognostic overshadowing, an entirely unanticipated bias in the clinical judgments of spiritual and multicultural psychologists.