Clinical, laboratory and radiological assessment of skeletal maturation in children and adolescents with obesity

Abstract

Background Childhood obesity is related to multiple serious health problems and an enhanced risk of premature onset of diseases. The relation of skeletal maturation to obesity is undetermined. The study aims to evaluate skeletal maturation in children and adolescents with obesity, to correlate it with their anthropometric data, body fat content, BMI, fat mass and pubertal stage. Results Our study shows that obese children and adolescents have accelerated skeletal maturation compared to control normal-weight healthy subjects (mean skeletal age difference of 0.123 ± 0.67 years versus − 0.175 ± 0.32 years). Also, there were significant positive correlations between bone age and BMI (r = 0.435, P value 0.00). Conclusion The mean skeletal age difference was more in the obese group as compared to the control group and suggesting accelerated skeletal development in the obese group. It is important to assess skeletal maturity in growing patients to determine the best timing for orthopedic and orthodontic treatment around the growth spurt.

Selenoprotein-p as Biomarker of Selenium Status in Obese Children and Adolescents

“…While substantially greater levels of HDL and TG (p = 0.001, p = 0.001). Ibrahim et al [31] study reported that no substantial variation in lipid profile among obese children and controls. While Mohammed et al, [21] study found that LDL and serum TC had been substantially greater among children with obesity as contrasted to control.…”