Clinical long-term outcome, technical success, and cost analysis of radiofrequency ablation for the treatment of osteoblastomas and spinal osteoid osteomas in comparison to open surgical resection

Weber, Marc‐André; Sprengel, Simon David; Omlor, Georg; Lehner, Burkhard; Wiedenhöfer, Bernd; Kauczor, Hans‐Ulrich; Rehnitz, Christoph

doi:10.1007/s00256-015-2139-z

Cited by 81 publications

(63 citation statements)

References 33 publications

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“…Radiofrequency ablation has been described as a potentially viable treatment option for spinal osteoblastomas as well, although this has not been widely used universally. 99 Methotrexate has been used as a chemotherapeutic agent within the same context as radiotherapy's use as an adjuvant treatment to surgical intervention. Others have also reported the use of polytherapy with doxorubicin, cisplatin, and methotrexate.…”

Section: Adjuvant Therapymentioning

confidence: 99%

Osteoblastomas of the spine: a comprehensive review

Galgano¹,

Goulart²,

Iwenofu

et al. 2016

FOC

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Osteoblastomas are primary bone tumors with an affinity for the spine. They typically involve the posterior elements, although extension through the pedicles into the vertebral body is not uncommon. Histologically, they are usually indistinguishable from osteoid osteomas. However, there are different variants of osteoblastomas, with the more aggressive type causing more pronounced bone destruction, soft-tissue infiltration, and epidural extension. A bone scan is the most sensitive radiographic examination used to evaluate osteoblastomas. These osseous neoplasms usually present in the 2nd decade of life with dull aching pain, which is difficult to localize. At times, they can present with a painful scoliosis, which usually resolves if the osteoblastoma is resected in a timely fashion. Neurological manifestations such as radiculopathy or myelopathy do occur as well, most commonly when there is mass effect on nerve roots or the spinal cord itself. The mainstay of treatment involves surgical intervention. Curettage has been a surgical option, although marginal excision or wide en bloc resection are preferred options. Adjuvant radiotherapy and chemotherapy are generally not undertaken, although some have advocated their use after less aggressive surgical maneuvers or with residual tumor. In this manuscript, the authors have aimed to systematically review the literature and to put forth an extensive, comprehensive overview of this rare osseous tumor.

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Section: Adjuvant Therapymentioning

confidence: 99%

Osteoblastomas of the spine: a comprehensive review

Galgano¹,

Goulart²,

Iwenofu

et al. 2016

FOC

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“…They are typically larger (Ͼ2 cm) and expansile with less sclerotic components compared with osteoid osteomas with thin peripheral sclerosis and may be associated with aneurysmal bone cyst. 43,44 On MR imaging, they demonstrate avid osseous and extraosseous enhancement. Spinal osteoblastomas compose approximately 40% of cases and often involve the posterior elements and are located in the cervical spine in 10%-40% of cases.…”

Section: 34mentioning

confidence: 99%

“…Most untreated lesions lead to painful scoliosis, and surgical excision has traditionally been the treatment of choice for spinal osteoblastomas, which is associated with morbidity, especially given the size of the osseous defect. 43,44 The entire osteolytic component and the soft-tissue component (if present) must be ablated for definitive cure. The imaging guidance (CT) and thermoprotective measures are similar to those in osteoid osteoma ablation.…”

Section: 34mentioning

confidence: 99%

“…26 Both RFA and laser ablation are also recommended for management of these lesions. 15,26,43,44 In case of RFA, considering lesion size, Ն2 ablations with straight unipolar probes should be performed to cover the entire lesion (90°C for 6 minutes each). Alternatively, a navigational bipolar RFA probe could be used to articulate the probe tip in different orientations through a single entry site, with precise determination of the size of the ablation zone by using built-in thermocouples.…”

Section: 34mentioning

confidence: 99%

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Benign Spine Lesions: Advances in Techniques for Minimally Invasive Percutaneous Treatment

Tomasian

Wallace

Jennings

2017

AJNR Am J Neuroradiol

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SUMMARY:Minimally invasive percutaneous imaging-guided techniques have been shown to be safe and effective for the treatment of benign tumors of the spine. Techniques available include a variety of tumor ablation technologies, including radiofrequency ablation, cryoablation, microwave ablation, alcohol ablation, and laser photocoagulation. Vertebral augmentation may be performed after ablation as part of the same procedure for fracture stabilization or prevention. Typically, the treatment goal in benign spine lesions is definitive cure. Painful benign spine lesions commonly encountered in daily practice include osteoid osteoma, osteoblastoma, vertebral hemangioma, aneurysmal bone cyst, Paget disease, and subacute/chronic Schmorl node. This review discusses the most recent advancement and use of minimally invasive percutaneous therapeutic options for the management of benign spine lesions. ABBREVIATIONS:PVA ϭ percutaneous vertebral augmentation; RF ϭ radiofrequency; RFA ϭ radiofrequency ablation

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“…Recently published studies indicated promising results, particularly for minimally-invasive treatment of osteoblastoma such that now RFA is currently regarded as the method of choice over surgical treatment [7,32]. Experiences regarding percutaneous thermal ablation of other bone tumors are limited and rely mainly on case reports or small case series, examples of which include the treatment of chondroblastoma [33], eosinophilic granuloma [34] or desmoid tumors [35].…”

Section: Rare Indicationsmentioning

confidence: 99%

Thermoablation of Bone Tumors

Ringe

Panzica

Falck

2016

Fortschr Röntgenstr

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The aim of this article is to review the significance of percutaneous thermal ablation in the treatment of bone tumors. We describe available ablation techniques as well as advantages and disadvantages in specific settings. In detail, radiofrequency ablation (RFA), microwave ablation (MWA), laser ablation, high intensity focused ultrasound (HIFU) and cryoablation are presented. In the second part of this review curative and palliative indications for the treatment of benign and malignant bone tumors are discussed. This includes especially RFA, laser or cryoablation for the treatment of osteoid osteoma, as well as the palliative treatment of painful bone metastases, for example, by means of MWA or MR-guided HIFU. Key Points: ??The various thermoablative techniques demonstrate specific advantages and disadvantages. ??Radiofrequency ablation is the evidence-based method of choice for treating osteoid osteoma. ??Laser ablation is primarily suited for the treatment of small lesions of the hands and feet. ??The intrinsically analgesic effect of cryoablation is advantageous when treating painful lesions. ??Palliative treatment of painful bone metastases can for example be performed using MWA or MR-guided HIFU, by itself or combined with cementoplasty. Citation Format: ??Ringe KI, Panzica M, von Falck C. Thermoablation of Bone Tumors. Fortschr R?ntgenstr 2016; 188: 539???550

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Clinical long-term outcome, technical success, and cost analysis of radiofrequency ablation for the treatment of osteoblastomas and spinal osteoid osteomas in comparison to open surgical resection

Abstract: RFA is an efficient method for treating OB and spinal OO and should be regarded as the first-line therapy after interdisciplinary individual case discussion.

Cited by 81 publications

References 33 publications

Osteoblastomas of the spine: a comprehensive review

Osteoblastomas of the spine: a comprehensive review

Benign Spine Lesions: Advances in Techniques for Minimally Invasive Percutaneous Treatment

Thermoablation of Bone Tumors

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