2023
DOI: 10.12998/wjcc.v11.i13.2903
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Clinical management of dural defects: A review

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Cited by 9 publications
(3 citation statements)
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“…Macrophages possess potent phagocytosis and a lethal capacity, which could swiftly reach the site of infection by penetrating the blood vessel wall through chemotactic media, carrying out the biological processes of microorganism digestion and phagocytosis. 44 Due to the considerable rise in basophila and macrophage levels in CSF, the rabbit brain with dural defect might have been infected with bacteria. Overall, the n HA/PLCL membrane could effectively stop intracranial infections and inflammatory reactions brought on by dural injuries.…”
Section: Resultsmentioning
confidence: 99%
“…Macrophages possess potent phagocytosis and a lethal capacity, which could swiftly reach the site of infection by penetrating the blood vessel wall through chemotactic media, carrying out the biological processes of microorganism digestion and phagocytosis. 44 Due to the considerable rise in basophila and macrophage levels in CSF, the rabbit brain with dural defect might have been infected with bacteria. Overall, the n HA/PLCL membrane could effectively stop intracranial infections and inflammatory reactions brought on by dural injuries.…”
Section: Resultsmentioning
confidence: 99%
“…When the dura is torn or damaged, the decrease in cerebrospinal fluid (CSF) pressure leads to a series of clinical symptoms often followed by complications such as infections and neurological dysfunction. 9 The first action to take is to rinse thoroughly with saline solution (∼500 mL) to assess the extent of the damage and discuss with the veterinarian the possibility of suturing the dura. Instead, Gelfoam (absorbable gelatin compressed sponge) can be used to cover a small dural incision.…”
Section: Troubleshootingmentioning
confidence: 99%
“…The hermetic closure of the dura mater is an essential step in the training of any neurosurgeon; it is an extremely important moment, often undervalued by neurosurgeons in training. The consequence of inadequate closure, often due to insufficient training, can lead to serious complications, such as cerebrospinal fluid (CSF) leak with consequent meningitis and even death [ 1 , 2 ]. Among the complications in neurosurgery, CSF leak is one of the most challenging, often leading to prolonged hospitalization and reoperation.…”
Section: Introductionmentioning
confidence: 99%