Objective: To evaluate the allergic effects of the residual monomer by using auto polymerised acrylic resins amongst dentists. Study Design: Cross Sectional study. Setting: Department of Prosthdontics, Isra Dental College, Hyderabad. Period: June 2019 to October 2019. Material & Methods: The study consists of 50 participants included Prosthodontist specialists, general dental practitioners and dental students. All contributors that filled a questionnaire regarding the allergic effects after using auto polymerised poly methyl methacrylate resin, identity of all participants will be kept private after taking consent. In questionnaire asked the questions from the contributors regarding the designation, qualification, usage duration, organs affected by allergy by using poly methyl meth acrylate resin, any medical treatment acquired for allergy and what kind of precautions used for prevention of allergy. Data was analyzed thru SPSS version 21. Descriptive statistics such as frequency distribution, percentage were included in Data analysis. The level of significance was set at <0.05%. Results: This current study discovered that out of 50 participants, 64% were students, 25% general dentists and 10% specialists. Out of 50 participants, maximum participants 45% found the skin allergic reaction and minimum 8% found respiratory tract. Only 10 participants acquired the treatment and consults the doctor for allergic reactions and 25 participants did not acquired any treatment. Conclusion: Conclusion of this study was that the maximum contributors had allergic effects to the skin while many participants did not acquired or followed any therapeutic service to avoid surplus effects.