Clinical Management of Liver Cancer in India and Other Developing Nations: A Focus on Radiation Based Strategies

Subramanian, Suresh; Mallia, Madhava B.; Shinto, Ajit; Mathew, Ashwathy Susan

doi:10.1007/s40487-021-00154-4

Cited by 3 publications

(1 citation statement)

References 128 publications

(169 reference statements)

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“…In this rural hospital setting, the study endeavours to address the need for improved diagnostic accuracy through a comprehensive analysis of clinical, ultrasonographic, and biochemical markers, coupled with the gold standard of histopathological examination. 4 This investigation holds particular significance given the unique patient demographics, healthcare infrastructure, and resource limitations characteristic of rural areas.…”

Section: Introductionmentioning

confidence: 99%

A correlational study to determine the correlation of clinical, ultrasonographic and biochemical markers with histopathological findings of various ovarian masses in rural hospitals

Sahu,

Shrivastava

2024

F1000Res

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Background Ovarian masses are a significant health concern among women, and their accurate diagnosis and characterization are paramount for effective management. This study protocol outlines a correlational investigation into the relationship between clinical, ultrasonographic, and biochemical markers and histopathological findings of ovarian masses in rural hospitals. Methods The study employs a correlational research design and will be conducted within the Department of Obstetrics and Gynecology at a rural hospital affiliated with Datta Meghe Institute of Higher Education and Research. The study population will comprise women of all ages diagnosed with ovarian masses. Clinical evaluations, ultrasonography, biochemical investigations, preoperative workup, and histopathological examinations will be conducted to gather data. The sample size will be determined based on statistical and practical considerations, yielding approximately 60 participants. Expected outcome The study expects to yield valuable insights into the diagnostic and prognostic indicators for ovarian masses. The data collected will enable the correlation of clinical symptoms, ultrasonographic findings, CA 125 levels, and histopathological characteristics, contributing to enhanced diagnostic accuracy, improved patient care, and potentially reduced healthcare costs in rural healthcare settings.

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Section: Introductionmentioning

confidence: 99%

A correlational study to determine the correlation of clinical, ultrasonographic and biochemical markers with histopathological findings of various ovarian masses in rural hospitals

Sahu,

Shrivastava

2024

F1000Res

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Treating liver cancer through arginine depletion

Prasad,

Anakha,

Pande

2024

Drug Discovery Today

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Patient Information Summarization in Clinical Settings: Scoping Review (Preprint)

Keszthelyi,

Gaudet-Blavignac,

Bjelogrlic

et al. 2022

Preprint

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BACKGROUND Information overflow, a common problem in the present clinical environment, can be mitigated by summarizing clinical data. Although there are several solutions for clinical summarization, there is a lack of a complete overview of the research relevant to this field. OBJECTIVE This study aims to identify state-of-the-art solutions for clinical summarization, to analyze their capabilities, and to identify their properties. METHODS A scoping review of articles published between 2005 and 2022 was conducted. With a clinical focus, PubMed and Web of Science were queried to find an initial set of reports, later extended by articles found through a chain of citations. The included reports were analyzed to answer the questions of where, what, and how medical information is summarized; whether summarization conserves temporality, uncertainty, and medical pertinence; and how the propositions are evaluated and deployed. To answer how information is summarized, methods were compared through a new framework “collect—synthesize—communicate” referring to information gathering from data, its synthesis, and communication to the end user. RESULTS Overall, 128 articles were included, representing various medical fields. Exclusively structured data were used as input in 46.1% (59/128) of papers, text in 41.4% (53/128) of articles, and both in 10.2% (13/128) of papers. Using the proposed framework, 42.2% (54/128) of the records contributed to information collection, 27.3% (35/128) contributed to information synthesis, and 46.1% (59/128) presented solutions for summary communication. Numerous summarization approaches have been presented, including extractive (n=13) and abstractive summarization (n=19); topic modeling (n=5); summary specification (n=11); concept and relation extraction (n=30); visual design considerations (n=59); and complete pipelines (n=7) using information extraction, synthesis, and communication. Graphical displays (n=53), short texts (n=41), static reports (n=7), and problem-oriented views (n=7) were the most common types in terms of summary communication. Although temporality and uncertainty information were usually not conserved in most studies (74/128, 57.8% and 113/128, 88.3%, respectively), some studies presented solutions to treat this information. Overall, 115 (89.8%) articles showed results of an evaluation, and methods included evaluations with human participants (median 15, IQR 24 participants): measurements in experiments with human participants (n=31), real situations (n=8), and usability studies (n=28). Methods without human involvement included intrinsic evaluation (n=24), performance on a proxy (n=10), or domain-specific tasks (n=11). Overall, 11 (8.6%) reports described a system deployed in clinical settings. CONCLUSIONS The scientific literature contains many propositions for summarizing patient information but reports very few comparisons of these proposals. This work proposes to compare these algorithms through how they conserve essential aspects of clinical information and through the “collect—synthesize—communicate” framework. We found that current propositions usually address these 3 steps only partially. Moreover, they conserve and use temporality, uncertainty, and pertinent medical aspects to varying extents, and solutions are often preliminary. CLINICALTRIAL

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Clinical Management of Liver Cancer in India and Other Developing Nations: A Focus on Radiation Based Strategies

Cited by 3 publications

References 128 publications

A correlational study to determine the correlation of clinical, ultrasonographic and biochemical markers with histopathological findings of various ovarian masses in rural hospitals

A correlational study to determine the correlation of clinical, ultrasonographic and biochemical markers with histopathological findings of various ovarian masses in rural hospitals

Treating liver cancer through arginine depletion

Patient Information Summarization in Clinical Settings: Scoping Review (Preprint)

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