Clinical management of nonpalpable or small breast masses by fine-needle aspiration biopsy (FNAB) under ultrasound guidance

Intraoperative Ultrasonographically Guided Excisional Biopsy or Vacuum-Assisted Core Needle Biopsy for Nonpalpable Breast Lesions

“…These advantages include increased patient comfort, reduced incidence of vasovagal reactions, 16 higher complete-excision rate (because the dimensions of the mass are more evident and the needle position can be visualized real time), reduced cost, no requirement for ionizing radiation, and rapid execution. 6,7 The techniques used for US-guided biopsy for diagnosis of nonpalpable breast lesions, which include fine needle aspiration biopsy (FNAB), 8,9,20 large-core needle biopsy (LCNB), 10,11,21-23 DVAB, 16 -18 and open surgical biopsy [12][13][14][15]24,25 were reviewed (Table 5). This comparison clearly demonstrates that DVAB, with completely excisional biopsy as possible, is the best diagnostic techniques for treatment of nonpalpable breast lesions.…”

“…6,7 US-guided biopsy for nonpalpable breast lesions can be performed rapidly using fine needle-aspiration cytology; however, its use is usually associated with a high percentage of inadequate specimens. 8,9 From a review of the literature, it appears that US-guided core needle biopsy can resolve the problem of inadequate specimens; however, the false-negative rate ranges from 3.6% to 10.9% 10,11 and the procedure is associated with underestimation and the need for reexcisional biopsy. 2 Intraoperative US-guided excisional biopsy (IUGE) is feasible for treatment of nonpalpable breast lesions, providing an accurate diagnosis and obviating wire-localization breast biopsy.…”

Breast cancer teams: the impact of constitution, new cancer workload, and methods of operation on their effectiveness

“…Diagnosis Two measures were used: that is, the proportion of new breast cancer patients attending hospital more than twice to achieve a diagnosis (Harcourt et al, 1998); and the proportion of new breast cancer patients who had an open biopsy to achieve a diagnosis (Okamoto et al, 1998).…”

Diagnostic accuracy of fine‐needle aspiration cytology in histological grade 1 breast carcinomas: are we good enough?

“…The literature reports sensitivity ranging from 65% to 98% and specificity ranging from around 60% to 100%. ( 1–23 ) When integrated into the assessment process, FNAC reduces the benign biopsy rate. ( 24 )…”