2020
DOI: 10.1007/s11684-020-0820-7
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Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19

Abstract: Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread around the world. However, approaches to distinguish COVID-19 from pneumonia caused by other pathogens have not yet been reported. We retrospectively analyzed the clinical data of 97 children with probable COVID-19. A total of 13 (13.4%) patients were confirmed positive for SARS-CoV-2 infection by nucleic acid RT-PCR testing, and 41 (42.3%) patients were found to be infected with oth… Show more

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Cited by 13 publications
(8 citation statements)
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“…In some case series, deterioration of the clinical picture wherein dyspnea, cyanosis, and the onset of acute respiratory distress syndrome (ARDS) emerged approximately 8-10 days after the onset of SARS-CoV-2 infection, which could rapidly progress to multiple organ failure and death (14). In a pediatric series of children with COVID-19, 30.8% presented shortness of breath that required oxygen supplementation and 23.1% were transferred to intensive care unit (ICU) for organ dysfunction (15). In another case series of 41 children hospitalized for COVID-19, 11 of these presented lung lesions compatible with a picture of interstitial pneumonia (16).…”
Section: Introductionmentioning
confidence: 99%
“…In some case series, deterioration of the clinical picture wherein dyspnea, cyanosis, and the onset of acute respiratory distress syndrome (ARDS) emerged approximately 8-10 days after the onset of SARS-CoV-2 infection, which could rapidly progress to multiple organ failure and death (14). In a pediatric series of children with COVID-19, 30.8% presented shortness of breath that required oxygen supplementation and 23.1% were transferred to intensive care unit (ICU) for organ dysfunction (15). In another case series of 41 children hospitalized for COVID-19, 11 of these presented lung lesions compatible with a picture of interstitial pneumonia (16).…”
Section: Introductionmentioning
confidence: 99%
“…As the consequence, the immune system of frontliners can be compromised due to continuous psychological distress and physical exhaustion thus made them vulnerable to COVID-19 infection. (Cai et al, 2020). Furthermore, according to a study was conducted in several city in China, specifically the province of Chongqing, the study found that, somatization was reported frequently (Xiaoming et al, 2020) with 42.7% among nurses frontliners experienced identifiable somatic symptoms such as headaches, lethargy, sore throats in regards to respond to their psychological stress burden .…”
Section: Literature Reviewmentioning
confidence: 99%
“…Вірусна інфекція знижує імунологічну реактивність організму та призводить до некротичних змін епітелію дихальних шляхів, відкриваючи доступ бактеріальній флорі. Збудниками пневмонії є пневмокок, стафілокок, стрептокок, гемофільна паличка, кишкова паличка, клебсієли, пневмоцисти, мікоплазма, хламіда [6,14,15] Таким чином у дітей хворих на гостру пневмонію спостерігається наступна картина у аналізі крові: лейкоцитоз, збільшену ШОЕ, під час рентгенологічного дослідження -вогнищеві та інфільтративні тіні в одній із легень.…”
Section: результати дослідження та їх обговоренняunclassified