Clinical manifestations of Behçet’s disease in a large cohort of Chinese patients: gender- and age-related differences

Li, Chaoran; Lu, Li; Wu, Xiuhua; Shi, Jing; Liu, Jinjing; Zhou, Jiaxin; Wang, Li; Tian, Xinping; Zeng, Xiaofeng; Zheng, Wenjie

doi:10.1007/s10067-020-05026-2

Cited by 11 publications

(11 citation statements)

References 18 publications

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“…This result agree with the results of those published studies ( (13) in Russia ; (15) in Finland). Another study in china (9) differ from this study which found that female more than genital ulcer than male. The explanation of This difference were probably due to that the difference in hormonal balance influences the development of clinical manifestation of BD with gender like genital ulcer.…”

Section: Discussioncontrasting

confidence: 97%

“…this study which finds that females had oral ulcers more than males. this result similar with results of those published studies ( (13) in Russia ; (9) in china & (10) in japan ). This study show (37.9 %) of patients with recurrent genital ulceration.…”

Section: Discussionsupporting

confidence: 93%

“…Regarding the clinical features of patients, this result show a high percentage of patients with oral ulcers (96.6%). This result agree with the results of those published studies ( 82.1% by (8) in oman ; 96.3% by (9) in china ; 91.2 % by (10) in japan ; 100% by (11) in magnolia ; 99% by (12) in korea ). Regarding the relationship between gender and oral ulcer.…”

Section: Discussionsupporting

confidence: 93%

“…This study show relationships between ocular lesion with gender. This result find that male had more than female , this result similar to the results of those reported studies ( (13) in Russia ; (9) in china ; (10) in japan ; (19) in Greek ; (11) in magnolia). Regarding the cutaneous manifestation , this study shows (62.1%) of patients with skin lesions.…”

Section: Discussionsupporting

confidence: 92%

“…this result similar with the result Omani study (8) which shows (40%) of patients with genital ulceration and also similar with another study conducted in Iran (14) that find (47.4%) of patients with genital ulcer. Another study in china (9) that results show differ from this study which finds that (71.2%) of patients had a genital ulcer. The explanation of This difference were probably due to differences in geographic regions, genetics or diagnostic criteria.…”

Section: Discussioncontrasting

confidence: 89%

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Common complications of Behcet’s Disease in Baghdad Teaching Hospital

Barq Wameedh Azeez,

Atta AH Al-Sarray,

Ali H. Al-Hafidh

2021

Indian Journal of Forensic Medicine & Toxicology

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Background: Behcet's disease is multi-systemic vasculitis, which usually is frequent oral & genital ulcerations as well as eye and skin lesions.Objectives: To determine the proportion of complications of BD & associated epidemiological variables.Patients and Methods : A cross-sectional study was conducted and performed in the Baghdad teaching hospital's Rheumatology unit and Dermatology and Venereology Center, involving ( 116) patients over the course of six months, beginning November 2nd and ending April 2nd, 2020. Results:The patients ranged in age from 13 to 64 years old at the time of the study. The mean age and SD was 35.08±10.46 and 70.7% from male while 29.3% from female. Recurrent oral ulceration, Recurrent genital ulceration, Eye lesion, Skin lesion, and Joint symptoms were the most common clinical manifestations of Behcet's disease, with 96.6 percent, 37.9%, 67.2 percent, 62.1 percent, and 75.9%, respectively. The most common Behcet's disease complication was ocular complication (34.5 percent), and the first major symptom of BD (94 percent) was oral ulcer. The age at onset of disease at (20-29) years with higher frequency (38.8%). Conclusion :Higher percentages of study sample had ocular complications (83%) while the lower percentage (2%) had gastrointestinal complication.Recommendations: More research is required to determine the etiology, enhance diagnosis precision, and develop new therapeutic strategies. To prevent visceral and ocular involvements, early diagnosis and treatment with the help of a dermatologist with extensive experience is essential.

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Section: Discussioncontrasting

confidence: 97%