Clinical Manifestations of Hyponatremia and Hypernatremia in Under-Five Diarrheal Children in a Diarrhea Hospital

Shahrin, Lubaba; Chisti, Mohammad Jobayer; Huq, Sayeeda; Nishath, Thamanna; Christy, Maria D.; Hannan, Anika; Ahmed, Tahmeed

doi:10.1093/tropej/fmv100

Cited by 29 publications

(56 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, a number of previous studies reported strong association of death with severe malnutrition, 9-11 hypoxemia, 3,12 hyponatremia, 13,14 and female sex. 14,15 …”

Section: Discussionmentioning

confidence: 93%

Risk Factors for Death in Bangladeshi Children Under 5 Years of Age Hospitalized for Diarrhea and Severe Respiratory Distress in an Urban Critical Care Ward

Alam

Ahmed

Sarmin

et al. 2017

Global Pediatric Health

Self Cite

View full text Add to dashboard Cite

Children with diarrhea hospitalized for respiratory distress often have fatal outcome in resource-limited settings, although data are lacking on risk factors for death in such children. We sought to evaluate clinical predictors for death in such children. In this prospective cohort study, we enrolled under-5 children with diarrhea admitted with severe respiratory distress to the intensive care unit of Dhaka Hospital of International Centre for Diarhoeal Disease Research, Bangladesh, from September 2014 through September 2015. We compared clinical and laboratory characteristics between study children those who died (n = 29) and those who survived (n = 62). In logistic regression analysis, after adjusting for potential confounders, the independent predictors for death in children hospitalized for diarrhea and severe respiratory distress were severe sepsis and hypoglycemia (P < .05 for all). Thus, recognition of these simple parameters may help clinicians identify children with diarrhea at risk of deaths in order to initiate prompt management for the better outcome, especially in resource-poor settings.

show abstract

“…However, a number of previous studies reported strong association of death with severe malnutrition, 9-11 hypoxemia, 3,12 hyponatremia, 13,14 and female sex. 14,15 …”

Section: Discussionmentioning

confidence: 93%

Risk Factors for Death in Bangladeshi Children Under 5 Years of Age Hospitalized for Diarrhea and Severe Respiratory Distress in an Urban Critical Care Ward

Alam

Ahmed

Sarmin

et al. 2017

Global Pediatric Health

Self Cite

View full text Add to dashboard Cite

show abstract

“…Die wesentliche Komplikation einer hyponatriämischen Dehydration ist die Entwicklung einer hyponatriämischen Enzephalopathie mit Hirnödem, erhöhtem Hirndruck, gestörter Perfusion und selten auch Hirnstammeinklemmung [86,133]. Aufgrund der Verwendung von hypotonen intravenösen Rehydrationslösungen kann es auch iatrogen während der Behandlung zur Hyponatriämie kommen [134] (siehe II.2.8).…”

Section: Ii21 Empfehlungunclassified

“…Bei einer AGE wird bereits aufgrund des Volumendefizits und Erbrechens vermehrt antidiuretisches Hormon (ADH) gebildet, sodass hypotone Lösungen bei AGE nicht geeignet sind und zur Prävention der Hyponatriämie 0,9 %ige NaCl-Lösung verwendet werden soll [133,135]. Die klinischen Symptome können unspezifisch sein und mit Übelkeit und Erbrechen nicht von den üblichen Symptomen der AGE unterscheidbar sein, aber bis hin zu Bewusstseinsstörungen und Krampfanfällen reichen [86]. In seltenen Fällen können Herzrhythmusstörungen oder auch ein neurogenes Lungenödem auftreten.…”

Section: Ii21 Empfehlungunclassified

S2k-Leitlinie „Akute infektiöse Gastroenteritis im Säuglings-, Kindes- und Jugendalter“ – AWMF Registernummer 068-003

et al. 2019

View full text Add to dashboard Cite

Leitlinie der Gesellschaft für pädiatrische Gastroenterologie und Ernährung (GPGE) gemeinsam mit der Deutschen Gesellschaft für Kinder-und Jugendmedizin (DGKJ), dem Berufsverband der Kinder-und Jugendärzte (BVKJ), der Deutschen Gesellschaft für pädiatrische Infektiologie (DGPI), der österreichischen Gesellschaft für Kinder-und Jugendheilkunde (ÖGKJ), der Deutschen Gesellschaft für Gastroenterologie, Verdauungs-und Stoffwechselstörungen (DGVS), dem Arbeitskreis "Krankenhaus & Praxishygiene" der AWMF und der Deutschen Gesellschaft für Pflegewissenschaft e. V. (DGPW)

show abstract

“…One author notes, "physicians who are anxious about a patient's problem may be tempted to do something-anything-decisive in order to diminish their own anxiety." 5 Severe electrolyte derangements are common in developing countries 6 but less so in the United States. A prospective pediatric dehydration study over 1 year in the United States demonstrated rates of 6% and 3% of hypo-and hypernatremia, respectively (n = 182).…”

Section: Why Physicians Might Think Electrolyte Testing Is Helpfulmentioning

confidence: 99%

Things We Do For No Reason: Electrolyte Testing in Pediatric Acute Gastroenteritis

Lind

Johnson

2017

Journal of Hospital Medicine

View full text Add to dashboard Cite

The "Things We Do for No Reason" (TWDFNR) series reviews practices which have become common parts of hospital care but which may provide little value to our patients. Practices reviewed in the TWDFNR series do not represent "black and white" conclusions or clinical practice standards, but are meant as a starting place for research and active discussions among hospitalists and patients. We invite you to be part of that discussion.

show abstract

Clinical Manifestations of Hyponatremia and Hypernatremia in Under-Five Diarrheal Children in a Diarrhea Hospital

Abstract: Early diagnosis and prompt management of hypo- and hypernatremia by identifying simple clinical predicting factors of these two conditions in diarrheal children <5 years of age is critically important to prevent deaths in such children, especially in resource-limited settings.

Cited by 29 publications

References 24 publications

Risk Factors for Death in Bangladeshi Children Under 5 Years of Age Hospitalized for Diarrhea and Severe Respiratory Distress in an Urban Critical Care Ward

Risk Factors for Death in Bangladeshi Children Under 5 Years of Age Hospitalized for Diarrhea and Severe Respiratory Distress in an Urban Critical Care Ward

S2k-Leitlinie „Akute infektiöse Gastroenteritis im Säuglings-, Kindes- und Jugendalter“ – AWMF Registernummer 068-003

Things We Do For No Reason: Electrolyte Testing in Pediatric Acute Gastroenteritis

Contact Info

Product

Resources

About