Clinical Meaning in Skin-specific Quality of Life Instruments: A Comparison of the Dermatology Life Quality Index and Skindex Banding Systems

Rogers, Anna A.; DeLong, Laura K.; Chen, Shuo

doi:10.1016/j.det.2011.11.010

Cited by 34 publications

(39 citation statements)

References 40 publications

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“…Although it is sensitive to the homogeneity of the sample distribution, it does not take patient responses into consideration . On the other hand, the anchor‐based method is based on patients’ ratings and is therefore thought to provide the best estimate of an individual's perspective …”

Section: Discussionmentioning

confidence: 99%

What do Vitiligo Impact Scale‐22 scores mean? Studying the clinical interpretation of scores using an anchor‐based approach

et al. 2018

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Section: Discussionmentioning

confidence: 99%

What do Vitiligo Impact Scale‐22 scores mean? Studying the clinical interpretation of scores using an anchor‐based approach

et al. 2018

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“…Self‐assessments of AD severity and burden included the self‐reported global AD severity question ‘Would you describe your atopic dermatitis or eczema as mild, moderate, or severe?’, in addition to patient‐reported outcomes related to AD, including Patient‐Oriented Scoring AD (PO‐SCORAD) index (range 0–103) and numeric rating scale for itch and sleep scores of PO‐SCORAD (range 0–10), Patient‐Oriented Eczema Measure (POEM) (seven questions; range 0–28) and Dermatology Life Quality Index (DLQI) (10 questions; range 0–30) . For all analyses of AD severity, scores were divided into three categories (clear, almost clear, mild; moderate; severe, very severe) using the respective previously reported severity strata …”

Section: Methodsmentioning

confidence: 99%

“…20 For all analyses of AD severity, scores were divided into three categories (clear, almost clear, mild; moderate; severe, very severe) using the respective previously reported severity strata. 19,21 Mental health was assessed using the Hospital Anxiety and Depression Scale anxiety (HADS-A) and depression (HADS-D) scores (seven items; range 0-21 per score). 22,23 Borderline and abnormal anxiety/depression scores were defined as ≥ 8 and ≥ 11, respectively.…”

Section: Methodsmentioning

confidence: 99%

Symptoms and diagnosis of anxiety and depression in atopic dermatitis in U.S. adults

et al. 2019

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SummaryBackgroundThe relationship between atopic dermatitis (AD), anxiety and depression in the U.S. adult population is not well established.ObjectivesTo determine the relationship of AD and its severity with symptoms and diagnosis of anxiety and depression in U.S. adults.MethodsA cross‐sectional, population‐based study of 2893 adults was performed. AD was determined using modified U.K. Diagnostic Criteria.ResultsAdults with AD vs. those without AD had higher mean Hospital Anxiety and Depression Scale anxiety (HADS‐A) (7·7 vs. 5·6) and depression (HADS‐D) (6·0 vs. 4·3) scores and higher prevalences of abnormal (≥ 11) HADS‐A (28·6% vs. 15·5%) and HADS‐D (13·5% vs. 9·0%) scores. In multivariable linear and logistic regression models controlling for sociodemographics, AD was associated with significantly higher mean HADS‐A and HADS‐D scores (7·7 and 6·0) and higher odds of abnormal HADS‐A [odds ratio (OR) 2·19, 95% confidence interval (CI) 1·65–2·91] and HADS‐D scores (OR 1·50, 95% CI 1·04–2·17) (P ≤ 0·03 for all). Mean and abnormal HADS‐A and HADS‐D scores were increased in moderate and severe/very severe self‐reported global AD severity, Patient‐Oriented Eczema Measure (POEM), Patient‐Oriented Scoring AD (PO‐SCORAD), PO‐SCORAD itch and sleep (P < 0·0001 for all). All respondents with severe PO‐SCORAD, POEM and PO‐SCORAD itch had borderline or abnormal HADS‐A and HADS‐D scores. Adults with AD vs. those without AD had higher prevalence of self‐reported healthcare‐diagnosed anxiety or depression in the past year (40·0% vs. 17·5%). Many adults with AD who had borderline and/or abnormal HADS‐A or HADS‐D scores reported no diagnosis of anxiety or depression.Conclusions AD is associated with significantly increased anxiety and depression, which may go undiagnosed. What's already known about this topic? Previous studies found higher rates of anxiety and depression in clinical cohorts of patients with atopic dermatitis. What does this study add? This study found dramatically higher rates of anxiety and depression among adults with atopic dermatitis in the U.S. population, which was primarily driven by atopic dermatitis severity.Anxiety and depression often go undiagnosed in adults with atopic dermatitis.

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“…Dermatology Life Quality Index (DLQI) is the most common QOL instrument used in phase 2 and 3 clinical trials of psoriasis (Table 3) 11,12 . However, DLQI is a generic dermatology QOL measure that is not specific to psoriasis and does not adequately identify the unique QOL of psoriatic disease.…”

Section: Rheumatologymentioning

confidence: 99%

Psoriasis Outcome Measures: A Report from the GRAPPA 2012 Annual Meeting

Gottlieb

Armstrong

2013

J Rheumatol

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Psoriasis is a multisystem disease. The cutaneous and musculoskeletal manifestations (psoriatic arthritis) are well recognized. However, the other manifestations of psoriatic disease including metabolic syndrome, atherosclerotic cardiovascular disease, depression, poor self-esteem, and self-destructive habits including obesity, smoking and excess alcohol consumption are underappreciated. At the 2012 annual meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), members addressed the need to develop uniform, validated, standardized outcome measures for psoriatic disease, measures that are useful to all stakeholders including patients, physicians, regulators, and payers.

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Clinical Meaning in Skin-specific Quality of Life Instruments: A Comparison of the Dermatology Life Quality Index and Skindex Banding Systems

Cited by 34 publications

References 40 publications

What do Vitiligo Impact Scale‐22 scores mean? Studying the clinical interpretation of scores using an anchor‐based approach

What do Vitiligo Impact Scale‐22 scores mean? Studying the clinical interpretation of scores using an anchor‐based approach

Symptoms and diagnosis of anxiety and depression in atopic dermatitis in U.S. adults

Psoriasis Outcome Measures: A Report from the GRAPPA 2012 Annual Meeting

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