Clinical, microscopical and biochemical investigation of synovial fluid from temporomandibular joints

Kopp, Sigvard; Wenneberg, Bengt; Clemensson, Elisabet

doi:10.1111/j.1600-0722.1983.tb00772.x

Cited by 23 publications

(18 citation statements)

References 14 publications

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“…The most common radiographic features, in agreement with earlier studies (Ronning et al, 1974;Kahrulahti et al, 1990;Kreiborg etal, 1991, Olsson etal, 1991, were erosions of the cortical outline, indicating inflammatory TMJ involvement (Kopp, Wenneberg & Clemensson, 1983), and flattening, which is a sign of 'healing' and remodelling of the joint (Wenneberg, Kopp & Grondahl, 1991;Pharoah, 1994). These radiographic changes were strongly correlated to pain on mandibuiar movement, restriaed mouth opening capacity and long duration of the disease, indicating the important role of the systemic factors in the development of signs and symptoms of TMD.…”

Section: Discussionsupporting

confidence: 87%

Bite force and temporomandibular disorder in juvenile chronic arthritis

Wenneberg¹,

Kjellberg

Kiliaridis

1995

J of Oral Rehabilitation

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The aim of this study was to investigate the functional condition of the stomatognathic system in children suffering from juvenile chronic arthritis, with respect to bite force and temporomandibular disorder in relation to radiographic abnormalities of the mandibular condyle, occlusal factors and systemic disease parameters. Thirty-five children with juvenile chronic arthritis were compared to 89 healthy children with an Angle Class I occlusion and 62 children with an Angle Class II malocclusion. Subjective symptoms and clinical signs of temporomandibular disorder and radiographic mandibular condylar changes were more common in children with juvenile chronic arthritis than in the two comparison groups. Maximal molar and incisal bite forces and maximal molar bite force endurance times were also significantly reduced in children with juvenile chronic arthritis. It is concluded that the differences between the groups are caused mainly by the systemic inflammatory disease itself, but a functional influence of weakened masticatory muscles cannot be excluded.

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Section: Discussionsupporting

confidence: 87%

Bite force and temporomandibular disorder in juvenile chronic arthritis

Wenneberg¹,

Kjellberg

Kiliaridis

1995

J of Oral Rehabilitation

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“…Both the subjective symptom and the clinical sign of impaired mobility of the mandible in the individuals of the AS group were correlated to radiographic signs of TMJ disease-that is, flattening, erosion, and sclerosis of the mandibular condyle. Erosion is generally considered to be a sign of inflammatory joint disease (17,18) and flattening and sclerosis signs of joint remodeling (19), the latter two being caused either by physiological aging of the joint or joint disease (20, 21). Downloaded by [University of Otago] at 17:58 25 July 2015 Table 5.…”

Section: Discussionmentioning

confidence: 99%

The temporomandibular joint in ankylosing spondylitis Correlations between subjective, clinical, and radiographie features in the stomatognathic system and effects of treatment

Wenneberg

Kopp

Hollender

1984

Acta Odontologica Scandinavica

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One hundred individuals with ankylosing spondylitis (AS) and a comparison group comprising 57 individuals without joint symptoms or disease were studied for correlations between subjective, clinical, and radiographic features in the stomatognathic system and the short-term effect of occlusal splint therapy. There was a correlation between radiographic findings in the temporomandibular joint (TMJ) and subjective and clinical symptoms from the stomatognathic system in individuals with AS but not in the comparison group. There were also more and stronger correlations between clinical signs of TMJ involvement and subjective and other clinical symptoms from the stomatognathic system in the individuals with AS than in the comparison group. There are thus strong indications that the subjective symptoms, the clinical signs, and the radiographic findings in the TMJ of the individuals with AS were caused mainly by this joint disease. The short-term effect of treatment with occlusal splints was investigated in seven of the individuals with AS, who had clinical dysfunction index II or more in accordance with Helkimo. No statistically significant improvement of the subjective or clinical symptoms from the stomatognathic system was found, although a reduction of clinical symptoms was noted in five of the seven individuals.

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“…convert extremely reactive free radicals to non-reactive molecular species (Vaille et al, 1989;Greenwald, 1991). In addition, most articular tissues, including those of the temporomandibular joint, normally contain transferrin, ceruloplasmin, albumin, haptoglobin, ascorbic acid, and tocopheral (vitamin E) (Kopp, 1983). Each of these molecules is capable of reducing the reactivity of free radicals by either direct or indirect mechanisms.…”

Section: (Iv) Mechanisms Of Degenerative Temporomandibular ]Oint Diseasementioning

confidence: 99%

Pathogenesis of Degenerative Joint Disease in the Human Temporomandibular Joint

Haskin

Milam²,

Cameron

1995

Critical Reviews in Oral Biology & Medicine

136

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ABSTRACT:The wide range of disease prevalences reported in epidemiological studies of temporomandibular degenerative joint disease reflects the fact that diagnoses are frequently guided by the presence or absence of non-specific signs and symptoms. Treatment is aimed at alleviating the disease symptoms rather than being guided by an understanding of the underlying disease processes. Much of our current understanding of disease processes in the temporomandibular joint is based on the study of other articular joints. Although it is likely that the molecular basis of pathogenesis is similar to that of other joints, additional study of the temporomandibular joint is required due to its unique structure and function. This review summarizes the unique structural and molecular features of the temporomandibular joint and the epidemiology of degenerative temporomandibular joint disease. As is discussed in this review, recent research has provided a better understanding of the molecular basis of degenerative joint disease processes, including insights into: the regulation of cytokine expression and activation, arachidonic acid metabolism, neural contributions to inflammation, mechanisms of extracellular matrix degradation, modulation of cell adhesion in inflammatory states, and the roles of free radicals and heat shock proteins in degenerative joint disease. Finally, the multiple cellular and molecular mechanisms involved in disease initiation and progression, along with factors that may modify the adaptive capacity of the joint, are presented as the basis for the rational design of new and more effective therapy.

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Clinical, microscopical and biochemical investigation of synovial fluid from temporomandibular joints

Cited by 23 publications

References 14 publications

Bite force and temporomandibular disorder in juvenile chronic arthritis

Bite force and temporomandibular disorder in juvenile chronic arthritis

The temporomandibular joint in ankylosing spondylitis Correlations between subjective, clinical, and radiographie features in the stomatognathic system and effects of treatment

Pathogenesis of Degenerative Joint Disease in the Human Temporomandibular Joint

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