Clinical outcome after endovascular, surgical or hybrid revascularisation in patients with combined carotid and coronary artery disease: the Finalised Research In ENDovascular Strategies Study Group (FRIENDS)

Abstract

Surgical and endovascular treatments yield very good immediate results; the later being less invasive, may be particularly suited to these fragile and complex patients. Long-term follow-up is under assessment.

Early and Long-Term Outcomes After Combined Percutaneous Revascularization in Patients With Carotid and Coronary Artery Stenoses

“…The FRIENDS study is the first large, multicenter registry including 659 patients with combined COD and CAD undergoing percutaneous, hybrid, or surgical revascularization treatments. The 30-day results of the overall population have been reported previously (15). This report presents the short-and long-term outcomes in the pre-specified subgroup of patients (n ϭ 239) undergoing a combined percutaneous revascularization.…”

Contemporary management of concomitant carotid and coronary artery disease

“…The primary composite endpoint of death, MI and stroke was seen in 4.8%, 2.4% and 8.6% among the three groups, respectively (p=0.01) 60. In conclusion, the authors reported very good results in the short term with the use of both surgical and endovascular strategies.…”

“…More recently, Ribichini60 published 30 day outcomes on 659 patients with concomitant carotid and coronary disease who were classified into three groups: surgical, endovascular and hybrid (defined as combination of surgical and endovascular intervention). The primary composite endpoint of death, MI and stroke was seen in 4.8%, 2.4% and 8.6% among the three groups, respectively (p=0.01) 60.…”

Simultaneous stenting of the left main coronary stem and internal carotid artery in a hemodynamically unstable patient

“…Advantages of this simultaneous approach compared with phase stenting include: higher comfort of the patient, and reduced incidence of complications related to puncture site, because femoral puncture is performed only once, and also cost-effectiveness because there is no need for repeated hospitalization 1 . Results of recently published multicentric, prospective, unrandomised study on 659 patients with coexistent coronary and carotid artery disease, strongly favor endovascular approach in treating these patients 11 . Adverse event rate (death, stroke or myocardial infarction) within thirty days was significantly lower among patients treated endovasculary in comparison with patients undergoing surgical or hybrid procedures.…”