Clinical Outcome of Breast Cancer BI-RADS 4 Lesions During 2003-2008 in the National Cancer Institute Thailand

Chaiwerawattana, Arkom; Thanasitthichai, Somchai; Boonlikit, Sarawan; Apiwanich, Chanin; Worawattanakul, Suvipapan; Intakawin, Anothai; Rakiad, Supattra; Thongkham, Kanchana

doi:10.7314/apjcp.2012.13.8.4063

Cited by 17 publications

(15 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, this was not completely in line with certain previous researches in which BI‐RADS score of 4 was mostly used as the cutoff value for benign and malignant lesions . Chaiwerawattana et al conducted a retrospective study of BI‐RADS 4 patients diagnosed in the National Cancer Institute Thailand during 2003‐2008, which showed that the malignant positive rates of 4A, 4B, and 4C patients were 7.7%, 38.7%, and 58.0%, respectively . In another study published by Elezaby et al, with 41 841 patients classified as BI‐RADS 4, the positive predictive values of 4A, 4B, and 4C patients were 7.6%, 22.0%, and 69.3%, respectively .…”

Section: Discussionmentioning

confidence: 89%

Contrast‐enhanced spectral mammography: A potential exclusion diagnosis modality in dense breast patients

et al. 2020

View full text Add to dashboard Cite

Background: China has an increasing burden of breast cancer. However, with a large population of dense breast patients, the diagnostic efficiency of conventional digital mammography is attenuated. Methods: From July 2017 to October 2018, we retrospectively reviewed 397 dense breast patients who underwent contrast-enhanced spectral mammography (CESM) in West China Hospital. Among them, 53 patients who had both CESM and dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) results and 114 patients who had pathological diagnoses were finally enrolled. All images were reviewed by two independent radiologists according to the 2013 Breast Imaging Reporting and Data System (BI-RADS) with all disagreements handed to an associate professor for final decisions. Correlation analyses between CESM and DCE-MRI were conducted. The diagnostic performance of CESM were investigated. Results: The kappa value of the BI-RADS scores between CESM and DCE-MRI was 0.607 (P < .001), indicating high correspondence between CESM and DCE-MRI. As for lesion size measurement, moderate correlation (Kendall's tau coefficient: 0.556, P < .001) was detected between CESM and DCE-MRI. Using pathological diagnoses as the reference standard, the sensitivity, specificity, and area under the curve (AUC) of CESM were 82.4%, 96.4%, and 0.894, respectively. Conclusion: CESM demonstrated excellent overall diagnostic accuracy and a moderate correlation in lesion size estimation against DCE-MRI in dense breast patients, supporting it to be an alternative to DCE-MRI in breast cancer detection and diagnosis, especially for exclusion diagnosis. K E Y W O R D S breast cancer, contrast-enhanced spectral mammography, diagnostic efficiency, dynamic contrastenhanced MRI, pathology How to cite this article: Qin Y, Liu Y, Zhang X, et al. Contrast-enhanced spectral mammography: A potential exclusion diagnosis modality in dense breast patients. Cancer Med. 2020;9:2653-2659. https ://doi.

show abstract

Section: Discussionmentioning

confidence: 89%

Contrast‐enhanced spectral mammography: A potential exclusion diagnosis modality in dense breast patients

et al. 2020

View full text Add to dashboard Cite

show abstract

“…In 2012, Chaiwerawattana et al compared BI-RADS 4 subgroups and attempted to detect differences between the subgroups in terms of survival rates [11]. They concluded that unnecessary biopsies could be avoided by accurate assessment of the subgroups.…”

Section: Discussionmentioning

confidence: 99%

Comparison of clinicopathological findings among patients whose mammography results were classified as category 4 subgroups of the BI-RADS

Leblebici

Bozkurt

Eren

et al. 2014

North Clin Istanbul

View full text Add to dashboard Cite

OBJECTIVE:Our aim is to compare mammographic, demographic and clinicopathological characteristics of patients whose mammographies were classified as subgroups of BI-RADS 4 category (Breast Imaging – Reporting and Data System).METHODS:In total, 103 patients with mammography (Senographe 600t Senix HF; General Electric, Moulineaux, France) results classified as BI-RADS 4 were included in the study. Demographic data (age, menopause, and family history) were recorded. All data were compared among BI-RADS 4 subgroups.RESULTS:In all, 68.9% (71/103), 7.8% (8/103) and 23.3% (24/103) the patients were in groups BI-RADS 4A, 4B and 4C, respectively. The incidence of malignancy was higher in Groups 4B and 4C than in Group 4A (p<0.05), but similar in Groups 4B and 4C (p>0.05). Mean age was lower in Group 4B than in Groups 4A and 4C (p<0.05). A positive family history was more common in Group 4A than in Group 4B (p=0.025). The frequency of menopausal patients was greater in Groups 4A and 4C than in Group 4B (p=0.021, and 0.003, respectively).METHODS:The rate of malignancy was higher in Groups 4B, and 4C than in Group 4A. A positive family history was more common in Group 4A than in Group 4C. Groups 4A, and 4C patients tended to be older and were more likely to be menopausal than Group 4B patients.

show abstract

“…BI‐RADS 4 category and its subgroups (i.e., A, B, and C) do not have well defined criteria and the reported malignancy rates for patients in this category show a very wide variation between 2% and 95%. Several recent studies have searched alternative approaches to reduce the false‐positivity associated with biopsy results in these patients including a short‐interval follow‐up schedule . In a multi‐center study by Bluemke et al.…”

Section: Discussionmentioning

confidence: 99%

Magnetic Resonance Imaging of the Breast as a Problem-solving Method: To Be or Not to Be?

Öztekin

Koşar

2014

Breast J

View full text Add to dashboard Cite

The use of dynamic magnetic resonance imaging (MRI) of the breast as a complementary problem-solving tool was explored in a heterogeneous population sample. A total of 3,076 patients that underwent breast MRI examination between January 2008 and June 2012 in our center were screened retrospectively. Of these, 868 met the following inclusion criteria and were considered eligible for the study: available data on clinical signs, symptoms and on the results of mammography and ultrasound examinations in medical records; at least 1 year of follow-up; and documented pathology findings. Lesions with a stable course over a follow-up period of at least 12 months were considered benign. MRI was suggestive of a suspicious abnormality (BI-RADS 4) or highly suggestive of malignancy (BI-RADS 5) in 129 (15%) of 868 patients, leading to a biopsy examination in these cases. On the other hand, MRI findings were considered normal in 739 (85%) subjects based on normal (BI-RADS 1), benign (BI-RADS 2) or probably benign (BI-RADS 3) findings. Of the 129 patients undergoing a histopathologic examination based on MRI findings, 63 were diagnosed with cancer, and in 66, the biopsy proved to be benign. Forty of the 63 patients (40/63) with a diagnosis of malignancy and 34 of the 66 patients (34/66) with a benign diagnosis had been categorized as BI-RADS 4 with conventional methods. A total of 23 patients with BI-RADS category of 0 to 3 according to conventional methods were diagnosed as having cancer with MRI. In six of these, the family history was positive. The sensitivity, specificity, positive predictive value, and negative predictive value (NPV) of MRI for the detection of cancer were 100%, 92%, 52%, and 100%, respectively. In cases with inconclusive findings on conventional imaging studies or in patients with clinical/radiological suspicion of malignancy, MRI should be more effectively used as a problem-solving approach owing to its high sensitivity and NPV in this condition. Use of MRI as a problem-solving method in such cases may decrease rather than increase unnecessary biopsy procedures and patient anxiety.

show abstract

Clinical Outcome of Breast Cancer BI-RADS 4 Lesions During 2003-2008 in the National Cancer Institute Thailand

Cited by 17 publications

References 15 publications

Contrast‐enhanced spectral mammography: A potential exclusion diagnosis modality in dense breast patients

Contrast‐enhanced spectral mammography: A potential exclusion diagnosis modality in dense breast patients

Comparison of clinicopathological findings among patients whose mammography results were classified as category 4 subgroups of the BI-RADS

Magnetic Resonance Imaging of the Breast as a Problem-solving Method: To Be or Not to Be?

Contact Info

Product

Resources

About