2017
DOI: 10.1016/j.brachy.2016.10.003
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Clinical outcome of high-dose-rate interstitial brachytherapy in vulvar cancer: A single institutional experience

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Cited by 22 publications
(19 citation statements)
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“…Of all the studies reviewed, only three salvage patients experienced severe treatment-related complications including one who developed a rectovaginal fistula and two who developed severe soft tissue necrosis ( 10 , 12 ). Mahantshetty et al also reported late toxicities in 22% including conservatively managed soft tissue necrosis, radiation proctitis, urethral stenosis, and skin and subcutaneous fibrosis ( 11 ). However, this was generalized for all patients and does not specify toxicity rates for salvage treatment.…”
Section: Discussionmentioning
confidence: 99%
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“…Of all the studies reviewed, only three salvage patients experienced severe treatment-related complications including one who developed a rectovaginal fistula and two who developed severe soft tissue necrosis ( 10 , 12 ). Mahantshetty et al also reported late toxicities in 22% including conservatively managed soft tissue necrosis, radiation proctitis, urethral stenosis, and skin and subcutaneous fibrosis ( 11 ). However, this was generalized for all patients and does not specify toxicity rates for salvage treatment.…”
Section: Discussionmentioning
confidence: 99%
“…However, 50% of patients relapsed with median time to failure of 31 months ( 10 ). Mahantshetty et al treated 38 patients, 3 of whom were treated for recurrent disease, and found 5-year overall survival, disease-free survival, and local control rates of 82, 51, and 77% respectively ( 11 ). Unfortunately, the specific results for salvage patients were not reported.…”
Section: Discussionmentioning
confidence: 99%
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“…Vulvo-vaginal cancers are rare with the average age of diagnosis 70 years and highest incidence in !90 years [62,63]. The use of brachytherapy boost in non-operable cases has been on the decline over the past decade despite improved disease specific survival and local control rates with combination treatment [64,65]. A small mixed case series in vaginal cancer showed a trend for improved outcome with combination treatment [66].…”
Section: Other Malignanciesmentioning
confidence: 99%