Clinical Outcome of Hydroxyapatite Coated, Bioactive Glass Coated, and Machined Ti6Al4V Threaded Dental Implant in Human Jaws

Mistry, Surajit; Roy, Rohan Basu; Kundu, Biswanath; Datta, Someswar; Kumar, Manoj; Chanda, Abhra; Kundu, Debtosh

doi:10.1097/id.0000000000000376

Cited by 29 publications

(35 citation statements)

References 28 publications

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“…Some of the experiments carried out so far have promising results [75,78], while others have focused on the use of HA, not as a coating, but in the form of “islands” in the titanium matrix, which would have the same effect and remove the adverse effects of the coating, while, on the other hand, increasing the positive effect on the development of bone tissue [72,80]. Some studies reveal a similar effectiveness of coatings using bioactive glasses for HA coatings [81,82].…”

Section: Dental Implantologymentioning

confidence: 99%

Hydroxyapatite and Fluorapatite in Conservative Dentistry and Oral Implantology—A Review

2019

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Calcium phosphate, due to its similarity to the inorganic fraction of mineralized tissues, has played a key role in many areas of medicine, in particular, regenerative medicine and orthopedics. It has also found application in conservative dentistry and dental surgery, in particular, as components of toothpaste and mouth rinse, coatings of dental implants, cements, and bone substitute materials for the restoration of cavities in maxillofacial surgery. In dental applications, the most important role is played by hydroxyapatite and fluorapatite, i.e., calcium phosphates characterized by the highest chemical stability and very low solubility. This paper presents the role of both apatites in dentistry and a review of recent achievements in the field of the application of these materials.

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Section: Dental Implantologymentioning

confidence: 99%

Hydroxyapatite and Fluorapatite in Conservative Dentistry and Oral Implantology—A Review

2019

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“…Functional recovery of the jaws using dental implants requires a minimum thickness and height of ridges 1 , 5 , 15 . Several factors culminate in the absence of alveolar bone, which then becomes a limiting factor for implant placement.…”

Section: Introductionmentioning

confidence: 99%

Bone repair access of BoneCeramic™ in 5-mm defects: study on rat calvaria

et al. 2018

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ObjectiveThe aim of this study was to evaluate the osteoconductive potential of BoneCeramic™ on bone healing in rat calvaria 5-mm defects.Material and MethodsA 5-mm calvaria bone defect was induced in three groups and the defect was not filled with biomaterial [Clot Group (CG)], autogenous bone (AG), or Bone Ceramic Group (BCG). Animals were euthanized after 14 or 28 days and the bone tissue within the central area of the bone defect was evaluated. Results were compared using ANOVA and Tukey test (p<0.05). Immunohistochemistry was performed using primary antibodies against osteocalcin, RUNX-2, TRAP, VEGF proteins, and 3-dimensional images of the defects in μCT were obtained to calculate bone mineral density (BMD).ResultsIn BCG, the defect was completely filled with biomaterial and new bone formation, which was statistically superior to that in the GC group, at both time-points (p<0.001 for 14 days; p=0.002 for 28 days). TRAP protein showed weak, RUNX-2 showed a greater immunolabeling when compared with other groups, VEGF showed moderate immunostaining, while osteocalcin was present at all time-points analyzed. The μCT images showed filling defect by BCG (BMD= 1337 HU at 28 days).ConclusionTherefore, the biomaterial tested was found to be favorable to fill bone defects for the reporting period analyzed.

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“…Additionally, bioactive glass and glass-ceramics coatings on Ti-based substrates were investigated [1,86,98,146,147,148,149,150,151,152,153,154].…”

Section: Deposition Methods and Physical Properties Of The Coatingsmentioning

confidence: 99%

Bioactive Glass and Silicate-Based Ceramic Coatings on Metallic Implants: Open Challenge or Outdated Topic?

2019

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The overall success and long-term life of the medical implants are decisively based on the convenient osseointegration at the hosting tissue-implant interface. Therefore, various surface modifications and different coating approaches have been utilized to the implants to enhance the bone formation and speed up the interaction with the surrounding hosting tissues, thereby enabling the successful fixation of implants. In this review, we will briefly present the main metallic implants and discuss their biocompatibility and osseointegration ability depending on their chemical and mechanical properties. In addition, as the main goal of this review, we explore the main properties of bioactive glasses and silica-based ceramics that are used as coating materials for both orthopedic and dental implants. The current review provides an overview of these bioactive coatings, with a particular emphasis on deposition methods, coating adhesion to the substrates and apatite formation ability tested by immersion in Simulated Body Fluid (SBF). In vitro and in vivo performances in terms of biocompatibility, biodegradability and improved osseointegration are examined as well.

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Clinical Outcome of Hydroxyapatite Coated, Bioactive Glass Coated, and Machined Ti6Al4V Threaded Dental Implant in Human Jaws

Abstract: Bioactive glass coated implants are equally safe and effective as hydroxyapatite coated and machined titanium implants in achieving osseointegration; therefore, can be effectively used as an alternative coating material for dental implants.

Cited by 29 publications

References 28 publications

Hydroxyapatite and Fluorapatite in Conservative Dentistry and Oral Implantology—A Review

Hydroxyapatite and Fluorapatite in Conservative Dentistry and Oral Implantology—A Review

Bone repair access of BoneCeramic™ in 5-mm defects: study on rat calvaria

Bioactive Glass and Silicate-Based Ceramic Coatings on Metallic Implants: Open Challenge or Outdated Topic?

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