Clinical outcome of platelet transfusion using platelet-rich plasma-derived platelets and buffy coat-removed platelets in patients with dengue fever – A comparison

Purushothaman, Jyothis; Innah, Susheela Jacob

doi:10.4103/gjtm.gjtm_9_20

Cited by 2 publications

(2 citation statements)

References 16 publications

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“…The woman, now in an isolation ward at the general hospital in Thrissur, is likely to be shifted to the Medical College Hospital there soon. Health officials were awaiting a result of one more test-Gene sequencing only after which it can be stated that the patient was affected with the virus [24]. Three others, who had returned from China, are also in isolation wards in Thrissur.…”

Section: Indiamentioning

confidence: 99%

Recent apprise on coronavirus and its terrible insinuations

et al. 2020

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Epidemically increased evidence reveals that the link between the 2019-nCoV and other similar strain of coronaviruses circulating in bats and specifically the Rhinopodous bat sub-species. These sub-species are ample and widely present in Southern China, Middle East Africa and Europe. Recent studies show that more than 500 CoV have been identified in bats in China. The Center for Diseases Control and Prevention and the World Health Organization maintains a website that is updated frequently with new cases of MERS-CoV infection. As per WHO Situation report 16th, 24,554 number of cases confirmed globally out of which 99.22% cases from china. A new coronavirus (2019-nCoV) is causing respiratory syndrome mostly in Hubei Province, China. Corona Virus spread over 24 countries including Japan, India, Korea, and other countries 2019-CoV infection vary from mild, moderate or severe illness; the later includes severe pneumonia, ARDS, sepsis and septic shock. There are two diagnostic tests for coronavirus infection i.e. molecular test and serology test. In this review article there are the various recent cases of the patients that are suffering from the corona virus, the outcome of these studies is that corona virus infection is an epidemic disease which affects Central Nervous System (CNS).

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Section: Indiamentioning

confidence: 99%

Recent apprise on coronavirus and its terrible insinuations

et al. 2020

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“…Platelet products available for transfusion are either random donor (RDP) or single-donor platelets apheresis (SDP).Platelet concentrate (PC) derived from whole blood donations can be either platelet rich plasma (PRP) or buffy coats from multiple donors, using different sequential centrifugation procedures [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Role of MicroRNA-326 and its Target Genes Bcl-xL and Bak as Potential Markers in Platelet Storage Lesion in Blood Banks

Elgendy

Swelem

Aboudiba

et al. 2022

Indian J Hematol Blood Transfus

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Platelet transfusion is crucial in the management of various conditions such as quantitative and qualitative platelet disorders. A serious problem that impacts public health is the shortage of Platelet concentrates (PCs) that frequently affect few blood donors’ countries, such as Egypt. This has necessitated the need to establish novel standards for determining the quality of PC during storage. It was found that microRNAs (miRNA) differential expression profile is a helpful tool for recognition of physiological platelet changes during storage. The aim of the current study was to highlight the role of platelet miRNA-326 and its putative target apoptotic genes, Bcl-xL and Bak, and their role in platelet storage lesion (PSL). Differential expression of miRNA-326 and its target genes in the apoptotic pathway, Bcl-xL and Bak was done using quantitative real time PCR (QR-PCR) on different storage points at day 0, day 3 and day 5 in blood bank. The results of the current study revealed over expression of miRNA-326 throughout days of storage resulted in down regulation of Bcl-xL gene and subsequently up regulation of Bak gene. MiRNA-326 contributes to platelet apoptosis and PSL through inhibition of anti-apoptotic Bcl-xL expression and enhancing pro-apoptotic Bak expression. Differential miRNA-326 and its target gene, Bcl-xL and Bak, expression levels at different points of platelets storage are promising tools as biomarkers for platelets undergoing PSL in blood banks.

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Clinical outcome of platelet transfusion using platelet-rich plasma-derived platelets and buffy coat-removed platelets in patients with dengue fever – A comparison

Cited by 2 publications

References 16 publications

Recent apprise on coronavirus and its terrible insinuations

Recent apprise on coronavirus and its terrible insinuations

Role of MicroRNA-326 and its Target Genes Bcl-xL and Bak as Potential Markers in Platelet Storage Lesion in Blood Banks

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