Clinical Outcomes after Percutaneous Vertebroplasty for Pathologic Compression Fractures in Osteolytic Metastatic Spinal Disease

Lim, Bong-Suk; Chang, Ung-Kyu; Youn, Sang-Min

doi:10.3340/jkns.2009.45.6.369

Cited by 30 publications

(22 citation statements)

References 14 publications

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“…Under these conditions, surgical intervention or conservative treatment including radiotherapy have been tried for local control. However, there are still debates on which therapeutic approach is optimal7,10,13,17). In particular, spinal cord compression by epidural myeloma with or without pathological fractures is a grave complication and, in this condition, timely optimal treatment is essential.…”

Section: Introductionmentioning

confidence: 99%

Multiple Myeloma and Epidural Spinal Cord Compression : Case Presentation and a Spine Surgeon's Perspective

Kim

2013

J Korean Neurosurg Soc

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Multiple myeloma, a multicentric hematological malignancy, is the most common primary tumor of the spine. As epidural myeloma causing spinal cord compression is a rare condition, its therapeutic approach and clinical results have been reported to be diverse, and no clear guidelines for therapeutic decision have been established. Three patients presented with progressive paraplegia and sensory disturbance. Image and serological studies revealed multiple myeloma and spinal cord compression caused by epidural myeloma. Emergency radiotherapy and steroid therapy were performed in all three cases. However, their clinical courses and results were distinctly different. Following review of our cases and the related literature, we suggest a systematic therapeutic approach for these patients to achieve better clinical results.

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Section: Introductionmentioning

confidence: 99%

Multiple Myeloma and Epidural Spinal Cord Compression : Case Presentation and a Spine Surgeon's Perspective

Kim

2013

J Korean Neurosurg Soc

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“…A recent prospective trial in noncancer VCF’s shows good efficacy, with significant reduction in pain and improved function 55 . Several smaller case series show good pain improvement with these procedures 56 …”

mentioning

confidence: 99%

23. Pain in Patients with Cancer

et al. 2011

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Pain in patients with cancer can be refractory to pharmacological treatment or intolerable side effects of pharmacological treatment may seriously disturb patients' quality of life. Specific interventional pain management techniques can be an effective alternative for those patients. The appropriate application of these interventional techniques provides better pain control, allows the reduction of analgesics and hence improves quality of life. Until recently, the majority of these techniques are considered to be a fourth consecutive step following the World Health Organization's pain treatment ladder. However, in cancer patients, earlier application of interventional pain management techniques can be recommended even before considering the use of strong opioids. Epidural and intrathecal medication administration allow the reduction of the daily oral or transdermal opioid dose, while maintaining or even improving the pain relief and reducing the side effects. Cervical cordotomy may be considered for patients suffering with unilateral pain at the level below the dermatome C5. This technique should only be applied in patients with a life expectancy of less than 1 year. Plexus coeliacus block or nervus splanchnicus block are recommended for the management of upper abdominal pain due to cancer. Pelvic pain due to cancer can be managed with plexus hypogastricus block and the saddle or lower end block may be a last resort for patients suffering with perineal pain. Back pain due to vertebral compression fractures with or without pathological tumor invasion may be managed with percutaneous vertebroplasty or kyphoplasty. All these interventional techniques should be a part of multidisciplinary patient program.

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“…(5) As to the patients with chronic obstructive pulmonary disease, the incidence of pulmonary embolism increases significantly, although intraoperative and postoperative blood gas analyses are implemented. (4) Considering the possibility of sudden cardiac arrest, transient hypotension, and disturbance of consciousness to the patients with heart diseases when undergoing a surgery in a prone position, electrocardiogram monitoring, or lateral-position surgery is suggested.…”

Section: Discussionmentioning

confidence: 99%

Research on Safety of Single-stage Multisegmental Thoracolumbar Percutaneous Balloon Vertebroplasty

Bao²

2014

Journal of Spinal Disorders &Amp; Techniques

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Clinical Outcomes after Percutaneous Vertebroplasty for Pathologic Compression Fractures in Osteolytic Metastatic Spinal Disease

Cited by 30 publications

References 14 publications

Multiple Myeloma and Epidural Spinal Cord Compression : Case Presentation and a Spine Surgeon's Perspective

Multiple Myeloma and Epidural Spinal Cord Compression : Case Presentation and a Spine Surgeon's Perspective

23. Pain in Patients with Cancer

Research on Safety of Single-stage Multisegmental Thoracolumbar Percutaneous Balloon Vertebroplasty

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