2023
DOI: 10.1017/ice.2022.314
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Clinical outcomes associated with blood-culture contamination are not affected by utilization of a rapid blood-culture identification system

Abstract: Objective: Contaminated blood cultures result in extended hospital stays and extended durations of antibiotic therapy. Rapid molecular-based blood culture testing can speed positive culture detection and improve clinical outcomes, particularly when combined with an antimicrobial stewardship program. We investigated the impact of a multiplex polymerase chain reaction (PCR) FilmArray Blood Culture Identification (BCID) system on clinical outcomes associated with contaminated blood cultures. Met… Show more

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“…Several studies shave investigated their use for invasive infections in adult populations. More rapid detection of contaminants in blood cultures with multiplex PCR did not improve length of hospital stay or average antibiotic duration in a recent observational study 1 . A pre–post observational study of the use of a rapid, direct blood culture pathogen identification using matrix‐assisted desorption ionisation time of flight mass spectrometry (MALDI‐TOF MS) found a significant reduction in time to effective and optimal antibiotic therapy 2 .…”
mentioning
confidence: 98%
“…Several studies shave investigated their use for invasive infections in adult populations. More rapid detection of contaminants in blood cultures with multiplex PCR did not improve length of hospital stay or average antibiotic duration in a recent observational study 1 . A pre–post observational study of the use of a rapid, direct blood culture pathogen identification using matrix‐assisted desorption ionisation time of flight mass spectrometry (MALDI‐TOF MS) found a significant reduction in time to effective and optimal antibiotic therapy 2 .…”
mentioning
confidence: 98%