Clinical Outcomes of Octogenarian Patients with Upper Gastrointestinal Bleeding

Abstract

Background: This study aimed to reveal whether there is any difference in clinical outcome between the octogenarian (>80 years old) and non-octogenarian patients in the geriatric patient group (>65 years old) with acute upper gastrointestinal bleeding. Methods: Patients aged 65 and over who were admitted with non-variceal upper gastrointestinal system bleeding included in the study. Patients in the study were divided into 2 groups, those aged 65-80 years and those over 80 years of age. Groups were compared in terms of laboratory findings, endoscopy findings, and serious clinical outcome. Results: The number of patients included in the study was 263 and their mean age was 78.25 ± 8.20 years. Comorbidity was present in 97.4% of the patients and in both groups the most common comorbid disease was hypertension. 28.5% of the patients were taking anticoagulants, 39.9% were taking antiplatelet drugs, and 18.6% were taking non-steroidal anti-inflammatory drugs. The median hospital stay of the patients was 5 days. In-hospital mortality was 5 (4.4%) and 6 (4.0%) and rebleeding was seen in 10 (8.8%) and 13 (8.7%) patients in the octogenarian and non-octogenarian groups, respectively. The frequency of patients who stayed in the hospital longer than 21 days was significantly higher in the octogenarian group compared to the other group (p=0.011). Conclusion: There was no significant difference in terms of in-hospital mortality, re-bleeding, need for intensive care, need for endoscopic intervention or hospital stay, but the frequency of prolonged hospital stay was significantly higher in the octogenarian group.