Introduction To compare the efficacy, safety, and complications of the trans-obturator mid-urethral sling (TO-TVT) and SolyxTM single-incision sling for treatment of female SUIMethods The clinical data of 92 patients who underwent urinary incontinence surgery in the Affiliated Hospital of Xuzhou Medical University were retrospectively analyzed. The groups were divided on surgical techniques such as TO-TVT and the Solyx single-incision sling groups. Preoperative evaluation included patient's history, urodynamic evaluation, clinical examination results, I-QOL, and UDI-6 scores. The operative time, intraoperative blood loss, complications, and hospital stay were recorded. At six months follow-up, the patient was re-evaluated for I-QOL, UDI-6 scores, and urodynamics and clinical examinations. The PGI-I questionnaire assessed subjective cure rates at six months postoperatively. Results Patients in the TO-TVT and Solyx single-incision sling groups had similar subject cure rates six months after surgery. There was no statistical significance in intraoperative blood loss, length of hospital stay, I-QOL and UDI-6 scores between the two groups except for operation time .There was no significant difference in the incidence of intraoperative and postoperative complications between the two groups.Conclusion In terms of the effect and complications, the TO-TVT is similar to SolyxTM single incision sling. Nevertheless, SolyxTM single incision sling is shorter in operation time, more minimally invasive, and has a definite curative effect worthy of clinical promotion.