Clinical-Pathological Conference Series from the Medical University of Graz

Clinical-Pathological Conference Series from the Medical University of Graz

“…The great majority of infections are either subclinical or mild and run a self-limiting anicteric course [8]. In about 10% of affected patients, infection leads to severe and possibly fatal Weil's disease, which is characterized by bleeding, renal failure and jaundice caused by intrahepatic cholestasis and direct hepatocyte damage [9,10]. The main route of acquiring leptospirosis is through mucosal membranes or percutaneous invasion by Leptospira excreted by carriers into the environment (e.g.…”