2024
DOI: 10.1002/jcla.25033
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Clinical Performance of Immunonephelometric Assay and Chemiluminescent Immunoassay for Detection of IgG Subclasses in Chinese

Yan Qin,
Yuhan Jia,
Congcong Liang
et al.

Abstract: BackgroundDetection of IgG subclasses (IgGSc) is vital for the diagnosis and management of disease, especially IgG4‐related diseases (IgG4‐RD). This study aimed to evaluate the performances of the chemiluminescent immunoassay (CLIA) for detecting IgGSc and diagnosing IgG4‐RD by IgGSc.MethodsA total of 40 individuals with IgG4‐RD, 40 with primary Sjogren's syndrome (pSS), and 40 healthy controls (HCs) were enrolled. Serum samples were collected for the simultaneous detection of IgG1, IgG2, IgG3, and IgG4 by the… Show more

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