2024
DOI: 10.1002/cpt.3241
|View full text |Cite
|
Sign up to set email alerts
|

Clinical Pharmacology Considerations for the “Off‐the‐Shelf” Allogeneic Cell Therapies

Hardik Mody,
Dhruvitkumar S. Sutaria,
Dale Miles

Abstract: Autologous chimeric antigen receptor T‐cell (CAR‐T) therapies have garnered unprecedented clinical success with multiple regulatory approvals for the treatment of various hematological malignancies. However, there are still several clinical challenges that limit their broad utilization for aggressive disease conditions. To address some of these challenges, allogeneic cell therapies are evaluated as an alternative approach. As compared with autologous products, they offer several advantages, such as a more stan… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 2 publications
references
References 67 publications
0
0
0
Order By: Relevance