CLINICAL PRACTICE: Essentials of Oxygenation: Implications for Clinical Practice

Parfitt, Janice M.

doi:10.1016/s0001-2092(07)64924-2

Cited by 2 publications

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“…The hemodynamic parameters were fixed to 5 L/min for blood flow to mimic standard human cardiac output, 11 magnetic stirrer to 400 rpm, and heating system to 38 °C.…”

Section: Methodsmentioning

confidence: 99%

New Biparietal Bipolar Catheter Prototype for Hybrid Atrial Fibrillation Ablation

Matteucci

Maesen

Asmundis

et al. 2021

Innovations�(Phila)

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Objective To evaluate the size and depth of linear lesions by in vitro testing with a custom-made radio frequency biparietal bipolar ablation catheter in a single-stage setting. Methods A custom-made catheter was created to generate linear lesions around the left atrium and pulmonary veins of an ex vivo pig. Two frames were made, 1 epicardial and 1 endocardial. A continuous copper braid electrode and an alignment system consisting of 2 parallel rows of neodymium magnets were embedded in a flexible plastic support. After 24 hours of formalin conservation, samples of the left atrium of a freshly slaughtered pig were sliced in a cryotome, thus obtaining a sequence of 100-µm thick layers extending from the endocardial to the epicardial side. After being digitized through a scanner, these layers were evaluated using morphometric computer software. For each slice, we evaluated the maximum length of the lesions, the maximum epicardial length, the maximum endocardial length, the total area of the lesion, and the total volume. Results Forty transmural lesions from 40 specimens were obtained. The results were the following (the number in parenthesis is the interquartile range in mm): lesion maximum length ( L MAX) was 7.297 mm (0.006), epicardial maximum length ( L EPI) was 7.291 mm (0.014), and endocardial maximum length was 7.291 mm (0.018). The total area and total volume were 1018.50 ± 36.51 mm2 and 101.85 ± 3.65 mm3, respectively. Conclusions Our prototype showed very promising results. The next step will be to enhance the design for clinical application.

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“…The hemodynamic parameters were fixed to 5 L/min for blood flow to mimic standard human cardiac output, 11 magnetic stirrer to 400 rpm, and heating system to 38 °C.…”

Section: Methodsmentioning

confidence: 99%

New Biparietal Bipolar Catheter Prototype for Hybrid Atrial Fibrillation Ablation

Matteucci

Maesen

Asmundis

et al. 2021

Innovations�(Phila)

View full text Add to dashboard Cite

show abstract

“…In the SBB group, we used two identical consoles for the simultaneous RF application. The simulator settings were fixed in 5 l/min of blood flow to mimic the human cardiac output [9], contact forces of 300 g each side, temperature at 38°C, and stirrer motor at 400 RPM.…”

Section: Methodsmentioning

confidence: 99%

Comparison between biparietal bipolar and uniparietal bipolar radio frequency ablation techniques in a simultaneous procedural setting

Matteucci

Maesen

Asmundis³

et al. 2020

J Interv Card Electrophysiol

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Purpose To make an in vitro evaluation of the lesion size and depth produced in two different sets of radio frequency energy bipolar delivery: simultaneous biparietal bipolar (SBB) and simultaneous uniparietal bipolar (SUB). Methods Two separate prototypes have been built for our purpose: one to be used in SBB mode and the other to be used SUB mode. Forty left atrium samples were taken from the hearts of freshly slaughtered pigs. They were ablated into a simulator ABLABOX, where blood flow, temperature, and contact force were controlled. After being sliced into a cryotome, the samples were digitalized by a flatbed scanner, and the images were analyzed by a computer morphometric software. Results Transmural lesions were achieved in 18/20 samples (90%) in SBB, while SUB showed transmurality in 9/20 samples (45%). Overall maximum diameter (DMAX) resulted larger in SUB than in SBB (2.43 ± 0.30 mm, 1.62 ± 0.14 mm, respectively; p < 0.05): Moreover, maximum epicardial and endocardial diameters (DEPI and DENDO, respectively) were wider in SUB group than SBB group (2.28 ± 0.30 mm, 2.26 ± 0.40 and 1.60 ± 0.14 mm, 1.59 ± 0.15 mm, respectively; p < 0.05). We observed the same tendency in lesion depth: The total area and volume (ATOT and VTOT) were broader in SUB group than in SBB one (581.01 ± 65.38 mm/mm2, 58.10 ± 6.53 mm/mm3 and 521.97 ± 73.05 mm/mm2, 52.19 ± 7.30 mm/mm3. respectively; p < 0.05). Conclusions In contrast with the smaller lesion sizes, the biparietal bipolar group showed a higher transmurality rate. These findings may suggest a better drive of the energy flow when compared with SUB lesions.

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CLINICAL PRACTICE: Essentials of Oxygenation: Implications for Clinical Practice

Abstract: CLINICAL PRACTICE: Essentials of Oxygenation: Implications for Clinical Practice, By Thomas Ahrens, Kim Rutherford, 1993, 194 pp $49.95 hardcover

Cited by 2 publications

References 0 publications

New Biparietal Bipolar Catheter Prototype for Hybrid Atrial Fibrillation Ablation

New Biparietal Bipolar Catheter Prototype for Hybrid Atrial Fibrillation Ablation

Comparison between biparietal bipolar and uniparietal bipolar radio frequency ablation techniques in a simultaneous procedural setting

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