Perioperative thromboprophylaxis strategy for neurosurgical procedures is beyond to be solved and it is a timeless matter of discussion among anaesthesiologists and neurosurgeons. At the end of 2015 we developed in our hospital a consensus protocol with the neurosurgical team, similar to the latest published recommendations. (1,2) Our aim was to analyse the effect of the protocol on thrombosis prophylaxis, detection and treatment.