Clinical predictors for mechanical ventilation and prognosis in patients with Guillian-Barre syndrome: a 10-year experience

Clinical predictors and electrodiagnostic characteristics in patients with Guillain-Barré syndrome with respiratory failure: a retrospective, matched case-control study

“…Regarding EDx results, we found no difference in GBS subtypes in the group with respiratory failure, which is consistent with some studies ( Green, Baker & Subramaniam, 2018 ; Parveen et al, 2020 ) but contradicts others where a higher proportion of demyelinating ( Durand et al, 2006 ; Yamagishi et al, 2017 ) or axonal GBS subtypes was found ( Shangab & Al Kaylani, 2021 ; Walgaard et al, 2010 ; Islam et al, 2019 ; Luo et al, 2020 ).…”

“…Additionally, we found a higher male-to-female ratio of 2.6:1 compared to 1.6:1 in overall GBS, suggesting that males might have a higher morbidity than females ( Kasemsap et al, 2021 ). This observation is different from a meta-analysis that revealed that men were no more likely to require MV ( Green, Baker & Subramaniam, 2018 ) but was consistent with previous studies in Bangladesh and the United Arab Emirates, which showed that 68–78% of ventilated patients were male ( Shangab & Kaylani, 2021 ; Islam et al, 2019 ). The seasonal prevalence of GBS was comparable to previous studies confirming that the rainy and winter seasons had significantly more patients ( Areeyapinan & Phanthumchinda, 2010 ; Kasemsap et al, 2021 ).…”

“…Compared to previous epidemiological studies in Thailand, our patients with respiratory failure were older (50.6 vs. 42.0–43.0 years), which correlates to previous findings in which the mortality rate in the older age group was higher than the younger age group (5.2% in patients age ≥ 65 years compared to 1.5% and 3.6% in patients age ≥ 18 and 19–64 years, respectively) ( Areeyapinan & Phanthumchinda, 2010 ; Kasemsap et al, 2021 ; Wen et al, 2021 ). Similarly, Shangab & Al Kaylani (2021) reported that older age at presentation is a major predictor for the need for mechanical ventilation (MV). Additionally, we found a higher male-to-female ratio of 2.6:1 compared to 1.6:1 in overall GBS, suggesting that males might have a higher morbidity than females ( Kasemsap et al, 2021 ).…”

“…Respiratory failure is a common complication of GBS, caused by respiratory muscle weakness and impaired secretion clearance ( Green, Baker & Subramaniam, 2018 ). The prevalence of respiratory failure in GBS ranges from 13.0–50.9% ( Malaga et al, 2021 ; Shangab & Al Kaylani, 2021 ; Sharshar et al, 2003 ; Sudulagunta et al, 2015 ; Toamad et al, 2015 ; Umer et al, 2019 ; Ning et al, 2020 ). According to a recent meta-analysis, the clinical risk factors for respiratory failure in patients with GBS are a short time from symptom onset to hospital admission, bulbar or neck weakness, and severe muscle weakness on admission ( Green, Baker & Subramaniam, 2018 ).…”

The early clinical and laboratory predictors of GBS outcome: hospital-based study, Assiut University, Upper Egypt

“…They found 65% patients had a high-risk score, 24% intermediate and 4% low-risk scores [27]. Shangab and their Colleagues found that 20 cases (24.4%) required MV at onset and axonal type was presented in 11 (55%) patients requiring intubation [38].Dysautonomia occurred in 19 patients (30.6%) and was significantly correlated with poorer outcomes in HDS and ONLS (P = 0.001, P = 0.001, respectively).…”