Clinical pregnancy after uterus transplantation

Akar, Münire Erman; Özkan, Ömer; Aydınuraz, Batu; Dırıcan, Enver Kerem; Cıncık, Mehmet; Mendilcioğlu, İnanç; Şi̇mşek, Mehmet; Günseren, Filiz; Koçak, Hüseyin; Çiftçioğlu, Akif; Geçici, Ömer; Özkan, Özlenen

doi:10.1016/j.fertnstert.2013.06.027

Cited by 153 publications

(82 citation statements)

References 53 publications

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“…The transplanted uterus was viable and the patient underwent embryo transfer 18 months after the operation, having presented two pregnancies spontaneously aborted before 6 weeks of gestational age (GA). 6 Initiated in 2012 in Sweden by the group of Dr. Brannstrom, the clinical trial on uterus transplant was responsible for the following nine cases in which nine patients, eight suffering from Rokytanski syndrome and one with prior hysterectomy due to cervical cancer, received transplants from living donors. Two patients underwent hysterectomy during the first few months after transplantation due to uterine artery thrombosis and severe intrauterine infection, respectively.…”

Section: Resultsmentioning

confidence: 99%

A meta-analysis on uterine transplantation: Redefining the limits of reproductive surgery

Silva

Carvalho

2016

Rev. Assoc. Med. Bras.

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SUMMARY In September 2014, the first baby grown in a transplanted uterus was born, which represented an astonishing scientific progress that will mark the history of human reproduction. The recipient was a 32-year-old woman with Rokytanski syndrome who became pregnant after a successful embryo transfer and had an uneventful pregnancy, giving birth to a healthy newborn and marking the beginning of a new era. Patients who do not have a uterus or have a dysfunctional uterus now have the chance of dreaming with pregnancy and motherhood. Combining principles of solid organ transplantation and techniques of human reproduction, uterus transplantation is the first ephemeral transplant performed in order to promote reproductive potential of women and may be removed after successful pregnancy. Worldwide, 11 uterine transplantations were performed in patients. Of these, seven maintained their reproductive potential, with viable transplanted uteri and regular menstrual cycles.

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Section: Resultsmentioning

confidence: 99%

A meta-analysis on uterine transplantation: Redefining the limits of reproductive surgery

Silva

Carvalho

2016

Rev. Assoc. Med. Bras.

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“…The first was a biochemical pregnancy, while the second time an abortion occurred prior to the eighth week. [8]. In this case, the uterus transplant was done from a brain dead female 22 years of age from whom other organs were also harvested.…”

Section: About the Authormentioning

confidence: 99%

Uterus Transplant: Does It Have Legs?

Hegde¹

2017

J Obstet Gynecol India

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“…Menstruation was reported after 20 days and the graft has so far survived with regular menstrual pattern without reported rejection episodes. Two early miscarriages after the first and second ET have been reported [52].…”

Section: Human Trialsmentioning

confidence: 99%