Clinical Presentation and Diagnosis of Papillary Thyroid Cancer

Papillary Thyroid Carcinoma: An Autobiographical Case Report

“…Total thyroidectomy with elective right neck dissection was planned due to the advanced size of the primary tumor and suspected lymph node involvement which is extremely common in PTC [ 1 , 2 , 4 ]. The primary tumor was first identified intraoperatively as seen in (Figure 2 ) and was sent to pathology for frozen as well as permanent sections as seen in (Figure 3 ).…”

“…The most common presentation of papillary carcinoma of the thyroid is an asymptomatic (painless) mass at the level of the thyroid. In around 20% of cases, patients may present with dysphagia or hoarseness which likely indicates involvement of the recurrent laryngeal nerve and/or tracheal compression [ 1 , 4 ]. These patients will often have normal thyroid function testing.…”

“…These patients will often have normal thyroid function testing. The diagnosis is made with ultrasound and fine-needle aspiration (FNA) [ 4 ]. Definitive treatment is surgical intervention with total thyroidectomy or lobectomy if the tumor is noted to be unifocal and < 4 cm without evidence of lymph node metastasis.…”

“…Definitive treatment is surgical intervention with total thyroidectomy or lobectomy if the tumor is noted to be unifocal and < 4 cm without evidence of lymph node metastasis. In those with advanced primary tumors, unilateral or bilateral neck dissection is indicated based on severity to evaluate the extent of local lymph nodes and for further staging [ 1 , 2 , 4 ]. Furthermore, neck dissections can be lateral compartment dissections or central compartment dissections, both of which have their own set of indications that are beyond the scope of this case report.…”

Taraxasterol inhibits TGF-β1-induced epithelial-to-mesenchymal transition in papillary thyroid cancer cells through regulating the Wnt/β-catenin signaling

“…[1][2][3] PTC is classified into conventional PTC (CPTC) and follicular variant PTC (FVPTC) and its diagnosis is generally based on nuclear features. [4][5][6][7] Currently, multiple therapeutic methods have been available for PTC treatment and a majority of PTC patients are accompanied by a good prognosis. [8][9][10] Unfortunately, there still are a small fraction of patients who develop local and distant metastasis and consequently suffer from a low survival rate.…”