Clinical Presentation and Management of Neonatal Malaria: A Review

Abstract

The burden of neonatal malaria was thought rare in the past because of presence of protective factors such as maternal antimalarial antibodies, lactoferrin, secretary IgA in human milk and HbF. In endemic areas for malaria, this group (neonates) needs to be more focused for such infection, as due to difficulty in diagnosis it may be representing only the tip of iceberg. In addition there is little information on the use of artimisinin-based combination therapy in neonates. This review aims to discuss all these aspects, focusing mainly on diagnosis and management of neonatal malaria. The final objective is to emphasize the need to establish management guideline of malaria in this neglected age group.

The Pattern of Severe Malaria in Plateau State of Nigeria: A Five-Year Review of Severe Malaria Case-Based Surveillance Data from 2013 to 2017

“…It was believed that the fetal hemoglobin provided some protection to the newborn against malaria [19]. This, however, is not the case as studies across Africa including Nigeria have shown neonatal malaria rates ranging from 0 to 54.2% [18][19][20][21].…”