Clinical Presentation and Treatment of Juvenile Idiopathic Arthritis Combined with Lung Disease: A Narrative Review

Juvenile Idiopathic Arthritis is Associated With Early Medical and Surgical Complications Following Primary Total Hip Arthroplasty: A National Database Study

“…Patients with JIA were at increased risk of several early medical complications, findings that are supported by the literature. JIA is associated with pulmonary complications such as pleurisy, and there are several reports of pneumonia, interstitial lung disease, and bronchiectasis [ 8 ]. Though renal involvement is rarely associated with JIA, it is possible that the underlying mild renal inflammation and nephrotoxic effects of treating medications coupled with postoperative renal dysfunction was the culprit for worsened renal function and failure [ 9 ].…”

Imaging of pulmonary fibrosis in children: A review, with proposed diagnostic criteria

“…37 While ILD is a relatively rare occurrence in JIA, the presence of ILD is associated with severe symptoms and a high mortality rate. 35,38 Pleuroparenchymal fibroelastosis (PPFE) is a rare disease causing dense fibrosis of the upper lungs for which the cause is uncertain, though it may be associated with a history of treatment for cancer (Figure 6). 39,40 PPFE and other forms of fibrosis have also been observed in children following lung transplantation.…”

“…Juvenile idiopathic arthritis (JIA) comprises a group of inflammatory disorders characterized by systemic symptoms and multiorgan damage 37 . While ILD is a relatively rare occurrence in JIA, the presence of ILD is associated with severe symptoms and a high mortality rate 35,38 . Pleuroparenchymal fibroelastosis (PPFE) is a rare disease causing dense fibrosis of the upper lungs for which the cause is uncertain, though it may be associated with a history of treatment for cancer (Figure 6).…”