Clinical presentation of maternal death with COVID-19 in rural tertiary care center: A retrospective-descriptive Study

Kurniawati, Devita; Prasetyo, Budi; Pandu, Hanindito; Nurdianto, Arif Rahman

doi:10.15562/bmj.v11i1.3158

Cited by 3 publications

(7 citation statements)

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“…There was one article that mentioned the increased risk of intubation and severe pneumonia (D'Antonio et al, 2021) Three studies mentioned the comorbidities found in patients. Almost all of the pregnant women aged >35 years had comorbidity (Djusad et al, 2021;Kurniawati et al, 2022;Shams et al, 2022). The most common comorbidity found was obesity.…”

Section: Resultsmentioning

confidence: 99%

“…There was an increase in mortality in the AMA group compared with the non-AMA group. Two studies found that almost all maternal death in advanced-age mothers were complicated by preeclampsia (Djusad et al, 2021;Kurniawati et al, 2022).…”

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…According to Kurniawati et al (2022), the CFR of maternal deaths caused by COVID-19 is 3.49%, and it is expected to rise as people get older. According to a study, CFR was 0.2% in the 20-29 age group, 1.3% in the 50-59 age group, and 15.6% in the 80 and above age group (Kurniawati et al, 2022). Two studies found that almost all maternal death in advanced-age mothers were complicated by preeclampsia (Djusad et al, 2021;Kurniawati et al, 2022).…”

Section: Discussionmentioning

confidence: 99%

“…According to a study, CFR was 0.2% in the 20-29 age group, 1.3% in the 50-59 age group, and 15.6% in the 80 and above age group (Kurniawati et al, 2022). Two studies found that almost all maternal death in advanced-age mothers were complicated by preeclampsia (Djusad et al, 2021;Kurniawati et al, 2022). Hypertension is known to be more likely in people who are older since endothelial damage gets worse with age.…”

Section: Discussionmentioning

confidence: 99%

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A Literature Review of Advanced Maternal Age in Pregnant Women with COVID-19

Hapsari¹,

Hermadiputri²,

Sa’adi³

2022

IJRP

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Background: During pregnancy, the risk of severe manifestation of COVID-19 with a worse maternal outcome can become higher because of the alteration in the immune system and physiological function. In COVID-19 infection, several studies also stated the increased risk of severe disease in advanced maternal age (AMA). Considering that the death and severe case rates in advanced-aged pregnant women with COVID-19 were high, special attention should be focused on this matter. There was still little study that focused on the outcome of COVID-19 in pregnant women with advanced age as well. Therefore, this study aims to evaluate the risks and the outcomes of advanced maternal age-pregnancy with COVID-19. Method: The method used in this paper is the Literature Review which aspires to analyze the risk and the outcome of COVID-19 in advanced maternal-age pregnancy. The databases used in the source search are PubMed, Google Scholar, JAMA, and AJOG. The keywords for the search were advanced maternal age, COVID-19, and pregnancy. Results: The mortality and morbidity of AMA who had COVID-19 were higher than non-AMA pregnant women. Severe conditions of COVID-19 were increased in AMA patients. They were at risk of having ICU admission and intubation. Advanced-aged mothers were more likely to have comorbidity including obesity. They also had a higher risk of adverse pregnancy outcomes. Conclusion:The adverse maternal aged-pregnant women with COVID-19 had higher risks of having comorbidities, severe conditions of COVID-19, adverse pregnancy outcomes, and mortality. Therefore, early risk identification needs to be done to identify the special management for the patients.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A Literature Review of Advanced Maternal Age in Pregnant Women with COVID-19

Hapsari¹,

Hermadiputri²,

Sa’adi³

2022

IJRP

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Untitled

2023

J. Med. Chem. Sci.

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Indonesia, like many other nations, has been significantly impacted by the COVID-19 disease since its emergence in late 2019. The first COVID-19 case in Indonesia was reported in March 2020, affecting people of all ages, races, and backgrounds, including pregnant patients. Pregnancy has been recognized as a co-morbidity for COVID-19 by the CDC. Among the various issues observed in COVID-19 patients, respiratory complications have been prevalent, leading to the widespread use of oxygen support and respiratory assistance devices. Patients with severe respiratory problems due to COVID-19 often require ventilators, and in cases requiring longterm ventilator support, ECMO (extracorporeal membrane oxygenation) is employed. This serial case report presents three cases of severe maternal COVID-19 that necessitated treatment with both ventilators and ECMO. In the first case, the patient was diagnosed with severe COVID-19 at 35/36 weeks of gestation. The second case involved a patient diagnosed with mild COVID-19 at 30/31 weeks of gestation. The last case featured a patient with moderate COVID-19 at 35/36 weeks of gestation. All three patients received ECMO after the termination of their pregnancies. The maternal outcomes varied among the cases, with the third case reporting a poor outcome due to the severe complications such as pulmonary hypertension and septic shock. However, the other two patients experienced manageable complications and had favorable maternal outcomes. Given the severity of the disease, gestational age, and associated complications, the impact of COVID-19 on pregnancy is still a subject of ongoing investigation. Appropriate management strategies should be pursued to improve outcomes for both mother and fetus.

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COVID-19: Maternal deaths in the tertiary health care center

Smruthi,

Rekha,

Manjula

et al. 2023

RHW

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The maternal mortality rate is increasing due to associated complications of labor, the severity of infection, and co-morbidities. The impact of COVID-19 infection on pregnant women data is insufficient in the literature, so in the present study, we are evaluating the rate of maternal mortality due to COVID-19 infection in McGANN Teaching District Hospital a tertiary health care center.The objective: to evaluate the rate of maternal mortality due to COVID-19 infection.Materials and methods. This is a single-center retro-prospective study, which included all maternal mortalities with COVID-19 infection admitted to the department of obstetrics and gynecology, McGANN teaching district hospital a tertiary health care center from June 2020 to October 2021. COVID-19 infected 15 pregnant women who died during hospitalization, treatment, labor, and after labor due to various complications. Data were collected from the medical record section and presented in an excel sheet and analyzed using SPSS software.Results. In the study period, maternal mortality due to COVID-19 infection was found to be more in the less than 30 years age group (73.3 %). Nearly all cases were admitted with complaints of fever (40 %), cough (53.3 %), abdominal pain (13.3 %), and breathlessness (80 %). Out of 15 maternal deaths, most of the cases are found to be primiparous (46.7 %), and the time from delivery to a death varies from 1-14 days. Nearly 66.7 % of cases had a gestational period of fewer than 36 weeks. Pulse rate, respiration rate, inflammatory markers, prothrombin time, liver enzymes, and blood glucose levels were elevated. The total protein hemoglobin and oxygen saturation percentage declined in the cases. The known co-morbidity present in the cases associated with maternal mortality was hypertension (20 %), diabetic mellitus (13.3 %), valvular heart disease (6.7 %), and pre-eclampsia (6.7 %). The most cause of death was acute respiratory distress syndrome (80 %).Conclusions. In this study the severe infection with co-morbidities showed an increased risk of severe morbidity and mortality.

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Clinical presentation of maternal death with COVID-19 in rural tertiary care center: A retrospective-descriptive Study

Cited by 3 publications

References 12 publications

A Literature Review of Advanced Maternal Age in Pregnant Women with COVID-19

A Literature Review of Advanced Maternal Age in Pregnant Women with COVID-19

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COVID-19: Maternal deaths in the tertiary health care center

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