Clinical Profile and Outcome of Patients with Dengue Syndrome in Hospital Care

Abstract

Dengue is a viral febrile illness, which has become a major international public health concern including Bangladesh, spectrum of illness ranging from dengue fever (DF) to life threatening dengue haemorrhagic fever (DHF), dengue shock syndrome (DSS) and ultimately death. The clinical profiling and outcome during epidemic dengue outbreak was observed in Dhaka Medical College Hospital in 2000 to 2001. One hundred and fifty patients were systematically observed. Male female ratio was 5:1 with severity of illness in younger patients. Hundred percent patients had fever with 83% having generalized weakness. The severe cases(DHF) were having sudden sustained temperature of 103 degree farenheight. Majority have abdominal symptoms(>80%) while 10% had respiratory only. Sixty percent have hepatomegaly while 40 % spleenomealy while 80% of DHF had ascites. Above 75% cases of Dengue haemorhagic fever had positive tourniquet test while melaena was the commonest mucosal bleeds. No fatality was observed in this study although variability of discharge was seen in different groups. Keyword: Clinical, Profile, Outcome, Dengue, Hospital DOI: http://dx.doi.org/10.3329/jom.v12i2.6733 JOM 2011; 12(2): 131-138

A retrospective study on the socio-demographic factors and clinical parameters of dengue disease and their effects on the clinical course and recovery of the patients in a tertiary care hospital of Bangladesh

“…A five-year (2013–2017) study displayed that complications from DHF/DSS were the major causes of death (65%) of dengue patients in Bangladesh and >70% of the deaths occurs within 24 hours of being admitted to the hospital [ 14 ]. Several studies have been performed to understand dengue epidemiology and clinical presentations in Bangladesh [ 15 – 17 ]. But recently, changing clinical patterns and unusual manifestations of dengue fever were reported [ 14 , 18 – 20 ].…”

Comparison of clinical manifestation of dengue fever in Bangladesh: an observation over a decade

“…Respiratory symptoms, gastrointestinal disorders, reduced platelet count, and abnormal liver function tests were also evident as presenting features of dengue now a day [9]. A temporal variation in the frequency of different clinical manifestations can be noted over the decade since the first outbreak [10][11][12][13][14] For example the outbreak of 2000 and 2002 were characterized by high-grade fever with typical purpuric rash, break-bone body ache, and thrombocytopenia [13,15], whereas in 2010 [12] and 2018 [11] outbreaks, predominant manifestations were fever, gastrointestinal symptoms and bleeding manifestation with normal platelet counts. Frequent transitions to plasma leakage leading to respiratory distress syndrome and organ dysfunction were more commonly observed and were considered a predicting factor of higher case fatality [12,13].…”

Clinical profile and prognosis of severe dengue infection in pediatric population admitted to tertiary care hospital

“…9 A temporal variation in the frequency of different clinical manifestations can be noted over the decade since the first outbreak. [10][11][12][13][14] For example the outbreak of 2000 and 2002 were characterized by high-grade fever with typical purpuric rash, break-bone body ache, and thrombocytopenia, whereas in 2010 and 2018 outbreaks, predominant manifestations were fever, gastrointestinal symptoms and bleeding manifestation with normal platelet counts. 15 Frequent transitions to plasma leakage leading to respiratory distress syndrome and organ dysfunction were more commonly observed and were considered a predicting factor of higher case fatality.…”