Clinical Profile of Botulinum Toxin A in Patients with Chronic Headaches and Cervical Dystonia

Abstract

This study demonstrated that botulinum toxin A is an effective and well tolerated preventive treatment for chronic headache in patients with cervical dystonia and a history of migraine. These results warrant further investigation in a large, randomized, controlled study.

Evidence to Use Botulinum Toxin Injections in Tension-Type Headache Management: A Systematic Review

“…The protocol of the systematic review is presented as a flow diagram in Figure 1 . Most studies have found that BTX can be very useful in TTH treatment [ 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 ]. There were also studies that did not support this thesis [ 21 ].…”

“…There were also studies that did not support this thesis [ 21 ]. A fact that the problem of TTH is associated mainly with the female gender is an interesting issue to mention [ 11 , 12 , 13 , 15 , 17 , 18 , 19 , 21 ].…”

“…In one study, the sample was composed only of children [ 10 ]. In most participants, TTH or CTTH was found [ 11 , 12 , 13 , 14 , 15 , 17 , 18 , 20 , 21 ]. In two studies, researchers also qualified patients with migraine [ 16 , 19 ].…”

“…Most studies reported a significant correlation between using BTX and a reduction in TTH pain intensity and severity [ 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 ]. Among described studies, some researchers proposed TTH treatment based on one injection session [ 11 , 12 , 13 , 14 , 15 , 18 , 19 ].…”

Headache Attributed to Craniocervical Dystonia – A Little Known Headache

“…Only 17 (71%) of the patients included concluded the study. It was concluded that BoNT probably had a beneficial effect with regard to reducing the patients' burden of headache and improving their quality of life, and also that the intensity and frequency of pain diminished in relation to the initial scores …”