Clinical Profile of Critical Pertussis in Children at a Pediatric Intensive Care Unit in Northern India

Kavitha, T; Samprathi, Madhusudan; Jayashree, Muralidharan; Gautam, Vikas; Sangal, Lucky

doi:10.1007/s13312-020-1756-3

Cited by 8 publications

(8 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Indeed, infant mortality rates due to pertussis ranges between 5.6% and 14.7% in the region [37]. In India, review of 36 pertussis cases admitted to the pediatric intensive care unit showed that 27.7% of those infected were infants below six weeks of age, the youngest age to receive the first dose of the tetanus-diphtheria-pertussis vaccine [36,38].…”

Section: Maternal Tdap Vaccinationmentioning

confidence: 99%

Maternal immunization: trends in South and Southeast Asian countries

Kamath

Kukreja

Mukherjee

et al. 2021

The Journal of Maternal-Fetal & Neonatal Medicine

View full text Add to dashboard Cite

Maternal immunization has the potential to reduce neonatal deaths caused by vaccine-preventable infectious diseases. Elimination of maternal and neonatal tetanus from many countries illustrates the potential benefits of maternal immunization as a strategy to decrease neonatal mortality caused by vaccine-preventable infections. Many countries in South and Southeast Asia have high cases of neonatal deaths, which were historically attributed to vaccine-preventable infections. Still, these countries vary in recommendations regarding immunization of pregnant women. We reviewed the current recommendations for the use of tetanus toxoid, tetanus-diphtheria, or tetanus-diphtheria-acellular pertussis (Tdap) vaccines for immunization of pregnant women. In addition to protection against tetanus and diphtheria, administration of the Tdap vaccine to pregnant women could help protect neonates against pertussis until they can receive the first two vaccine doses of their primary course. Vaccination against seasonal influenza is also recommended in many countries worldwide for pregnant women as influenza can pose health risks for the mother-fetus unit and the infant. Despite the recognized benefit of influenza vaccination for pregnant women, only some South and Southeast Asian countries have implemented its recommendation. The success of maternal tetanus vaccination has kindled the interest in vaccines that can be safely administered during pregnancy. Future availability of vaccines against respiratory syncytial virus and group B streptococcus, for use in pregnant women, could help prevent neonatal infections, especially in regions where diseases are less controlled. Communicating the body of evidence that supports maternal immunization to obstetricians is key for achieving optimal vaccination coverage to ensure protection of neonates. The current review aims to create awareness about the existing and potential benefits of maternal immunization in South and Southeast Asia.

show abstract

Section: Maternal Tdap Vaccinationmentioning

confidence: 99%

Maternal immunization: trends in South and Southeast Asian countries

Kamath

Kukreja

Mukherjee

et al. 2021

The Journal of Maternal-Fetal & Neonatal Medicine

View full text Add to dashboard Cite

show abstract

“…This is a case record review, with cases having been evaluated between December, 2018 and June, 2019 at a tertiary care pediatric center in Southern India. All children (up to 18 years) with first afebrile (apparently unprovoked) seizure presenting to emergency room were evaluated and treated as per standard protocol [1]. The necessary investigations like blood sugar, serum electrolytes, electroencephalography (EEG) and neuroimaging were done, with extent of evaluation varying on case-to-case basis, and treating physician's discretion.…”

Section: R R R R R E E E E E S S S S S E E E E E a A A A A R R R R R C C C C C H H H H H L L L L L E E E E E T T T T T T T T T T E E E E mentioning

confidence: 99%

“…The pertussis vaccine is effective in preventing Bordetella pertussis infection and death, and the risk is high in young infants who do not receive the vaccine [1]. B. pertussis infection in siblings is considered a common route of transmission to young infants [2].…”

Section: Pertussis Epidemic In Lower-grade Schoolchildren Without Preschool Vaccination Boostersmentioning

confidence: 99%

“…Children who participated in the survey were also asked to suggest contacts that would be willing to participate. Pediatric symptom checklist (PSC) -youth, self-report shorter version consisting of 17 questions was used [1,2]. This is a validated method for screening for psychosocial problems of school-aged children.…”

Section: Abstract: Psychosocial Wellness Covid-19mentioning

confidence: 99%

See 1 more Smart Citation

Research Letters

et al. 2020

View full text Add to dashboard Cite

Many common household herbal preparations may have seizurogenic ingredients. We report 15 children with seizures following exposure to such compounds: oral ingestion of liquid preparation in 13, and local application of balm and Eucalyptus oil ingestion in one each. All children, except one, had generalized seizures. This study highlights the need to address this history during evaluation of first seizure, and increase awareness of seizurogenic potential of such preparations.

show abstract

“…Pakistan has achieved the Millennium Development Goal of reducing infant mortality [4][5] . The Sustainable Development Goals aim to reduce infant mortality to at least 12 per 1,000 live births by 2030 6 . The downward trend in mortality has been even more impressive so far, especially for infants with very low birth weight <500 g birth weight.…”

Section: Introductionmentioning

confidence: 99%

Outcome, Clinical Profile and Risk Factors for Mortality of Neonates Necessitating Mechanical Ventilation

Naseer¹,

Farrukh²,

Masood³

et al. 2021

PJMHS

View full text Add to dashboard Cite

Background: Assisted ventilation has turn out to be an essential part of the neonatal intensive care unit (NICU). It is one of the main methods of support in the ICU and undoubtedly influences the survival of sick newborns. Aims: 1. To investigate common indications for mechanical ventilation in newborns 2. To investigate factors influencing the outcome. Method: It is a descriptive study of 60 infants admitted to the Department of Pediatric Medicine in the ICU over a one-year period in the department of Paediatrics, Abbasi Shaheed Hospital. The information was gathered and analysed in a pre-designed format. Results: Of a total of 60 infants, 46 survived, 14 died, and one infant was discharged despite medical advice. 36 children were born vaginally, 20 were born via LSCS, and 4 via assisted delivery. Postnatal asphyxia was the most common ventilation indication in full-term newborns, while HMD was present in preterm infants. The best results were obtained in ventilated infants with MAS, with 100% survival, followed by apnoea in premature infants, perinatal asphyxia, and HMD. Pulmonary haemorrhage (48.3%) was the most common complication among deceased infants, followed by sepsis (28.3%) and shock (23.4%) with a significant p <0.05. There were no complications in 76.7% of the surviving infants. Conclusions: Among the many widely available variables studied in this study, maximum and mean peak inspiratory pressure (PIP or (PEEP), maximum respiratory rate, maximum mean airway pressure (MAP) and average ventilation demand was much greater among non-survivals in comparison to the survivors. Bicarbonate, PH and excess base have been found to be important determinants of mortality in ventilated newborns. Keywords: Indications, mechanical ventilation and Results

show abstract

Clinical Profile of Critical Pertussis in Children at a Pediatric Intensive Care Unit in Northern India

Cited by 8 publications

References 19 publications

Maternal immunization: trends in South and Southeast Asian countries

Maternal immunization: trends in South and Southeast Asian countries

Research Letters

Outcome, Clinical Profile and Risk Factors for Mortality of Neonates Necessitating Mechanical Ventilation

Contact Info

Product

Resources

About