Clinical Profile of Enteric Fever in Children

Laishram, Narendra; Singh, Pebam Arunkumar

doi:10.14260/jemds/2016/28

Cited by 12 publications

(19 citation statements)

References 5 publications

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“…33 In other study they had reported relative bradycardia and hepatomegaly as the most common sign. 43 During our study, all cases were positive for Widal. Blood culture was positive in 20% of cases.…”

Section: Discussionmentioning

confidence: 52%

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A study on clinical profile of typhoid fever in children

Devaranavadagi

Srinivasa

2017

Int J Contemp Pediatr

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Background: Typhoid fever is caused by Salmonella typhi. It is a major public health problem in India. Typhoid fever is endemic in many developing countries. Wide variations in the clinical manifestations of typhoid fever make its diagnosis a challenging task. This study was conducted to understand the wide range of clinical manifestations, complications and antibiotic sensitivity patterns of typhoid fever in children.Methods:Prospectively, 113 children admitted in pediatric unit with confirmed Typhoid fever from September 2015 to December 2016 at KIMS hospital, Bangalore were included. In each case, age, sex, presenting complaint, laboratory investigations and antibiotic sensitivity pattern are collected and analysed.Results: Out of 113 cases, 72 cases (63.8.1%) were males, 41 cases (36.2%) were females. The most common age group was 5-10 years. The most common symptom was fever, seen in 100% cases, followed by anorexia (61%), vomiting (44%) and abdominal pain (18%). The most common sign observed was toxic look in 68% of the cases, followed by coated tongue in 49% and hepatomegaly in 44%. Leucocytopenia was found in 34% of cases. Eosinopenia was found in 39% of cases. Anaemia was found in 16% of cases. Thrombocytopenia was found in 15% of cases. Blood culture was positive in 20% of cases. Use of municipal water for drinking was found in 65% of cases. Outside eating was found in 40% of cases. Unhygienic practices were found in 64% of cases. Duration of hospital stay varied from 3-10 days. No mortality reported.Conclusions:Typhoid fever is most commonly observed with unhygienic practices and eating of unhealthy outside food. This major public health issue can be tackled by bringing awareness among people regarding disease transmission and its various preventive measures.

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Section: Discussionmentioning

confidence: 52%

“…35 A study done by Banu et al also reported 28% culture positive cases. 43 Due to prior use of antibiotics, the culture positive cases are decreasing. Thus, need for relay on other serological tests for diagnosis of typhoid exists.…”

Section: Discussionmentioning

confidence: 99%

A study on clinical profile of typhoid fever in children

Devaranavadagi

Srinivasa

2017

Int J Contemp Pediatr

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“…8 However, Laishram et al reported coated tongue (80%) as the most common sign followed by Hepatomegaly (76%) and splenomegaly (38%). 12 In present study, 33.3% of the children with typhoid had white cell count less than 4000/c.mm. Absolute eosinopenia was found in 74.7% cases.…”

supporting

confidence: 44%

Clinical profile of typhoid fever in children at a tertiary care hospital: a cross sectional study

Siddiqui

Koppa

Kale

2017

Int J Contemp Pediatr

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Background: In endemic areas such as India, traditional signs and symptoms in enteric fever are not often observed. Unusual presentations lead to diagnostic dilemma and may delay the diagnosis of typhoid fever. The present study describes the clinical presentation of enteric fever at a tertiary care centre in Aurangabad district of Maharashtra.Methods: The study was a hospital based prospective observational study done in paediatric ward of MGM Medical College, Aurangabad over a period of 18 month starting from 1st November 2013 to 31st April 2015. The parents of the children were informed about the research and its objectives, and written informed consent was obtained from them. Prior approval was taken from institutional ethics committee. Children of age 2 -18 years who presented with fever of 5 days or more with clinical signs and symptoms suggestive of typhoid fever and positive Widal test or Typhidot tests were included in the study. The demographic and clinical features of the patients were described.Results: Total of 99 patients were included in the study. Majority of the children were between 2 - 7 year age group (45.4%). Out of 99 children, 57 were males and 42 were females. Majority of the cases were from urban areas accounting for 75%, which included urban slums. Drinking water source was tap water in 80% cases and bore well water in 20% cases. Only 36.4% of children had fever of less than one-week duration. 58.6% of the cases had fever of more than one week but less than two weeks. Continuous fever was noticed in majority of children (55.55%). All the children presented with fever as the main complaint (100%). Loss of appetite and headache were the next common complaints reported by 59.6% cases. Commonest sign noticed was toxic look (83.8%) followed by coated tongue (74.7%) and splenomegaly (61.6%). Hepatomegaly was also noted in 39.4% of cases.Conclusions: Clinical presentation in the study subjects was similar to available reports from literature.

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“…Endemicity in developing countries is attributed to the low standard of living, poor hygiene practices, poor sanitation, contaminated water sources, and lack of universal vaccination. In children, the common age group affected is between five to 19 years, but in some endemic areas of Asia, it is also common in children less than two years [ 2 ]. Clinical manifestations are non-specific, which may delay the diagnosis and treatment leading to fatal complications.…”

Section: Introductionmentioning

confidence: 99%

Clinical and Laboratory Profile of Enteric Fever in Children From a Tertiary Care Centre in Odisha, Eastern India

Behera¹,

Rup²,

Dash³

et al. 2021

Cureus

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Background: Enteric fever is a major health problem in developing countries. Varied clinical presentation leads to diagnostic dilemmas resulting in fatal complications. Objective: To determine the socio-demographic, clinical manifestations, complications, antibiotic sensitivity pattern, treatment, and outcome in hospitalized enteric fever patients. Methods: A retrospective case record analysis of hospitalized patients in the age group one to 14 years with a discharge diagnosis of enteric fever was done in a tertiary care centre of Odisha over a period of three years (January 2017 to December 2019). Results: Of 112 patients, 75% of children belonged to the six to 14 years age group with a mean age of 7.6 +/- 3.6 years and a male to female ratio of 1.66:1. The peak of cases was seen during the month of January to June with 94% of cases occurring in low and middle socioeconomic status. The commonest presentation was fever in 98.21%; other features were vomiting (39.29%), pain in abdomen (21.43%), diarrhoea (26.79%), and anorexia (14.29%). Eosinopenia was found in 58.93%, transaminitis in 30.36%, and raised CRP in 73.21%. In 30 children blood culture was positive with sensitivity to third-generation cephalosporin. All isolates were nalidixic acid-resistant Salmonella Typhi (NARST). Complications were seen in 21.42%. All recovered and two left against medical advice. Conclusion: Enteric fever is a major threat in the paediatric age group. Early clinical diagnosis with rational use of antibiotics according to sensitivity pattern is important. Improved hygiene, vaccination, and awareness among people is necessary for prevention.

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Clinical Profile of Enteric Fever in Children

Cited by 12 publications

References 5 publications

A study on clinical profile of typhoid fever in children

A study on clinical profile of typhoid fever in children

Clinical profile of typhoid fever in children at a tertiary care hospital: a cross sectional study

Clinical and Laboratory Profile of Enteric Fever in Children From a Tertiary Care Centre in Odisha, Eastern India

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