Clinical Profile of Febrile convulsion among admitted children in a tertiary care hospital at Dhaka city

Abstract

Background : Febrile convulsion (FC) is the most common type of seizure that occurs in children aged 4-60 months, which is benign and had a good prognosis.Objective : To evaluate the clinical profile and management of hospitalized children with Febrile convulsion.Methodology : This cross sectional study was done in Dhaka Shishu (children) Hospital during July 01, 2013 to June 30, 2014. Total 80 children aged between 4-72 months who were admitted in to Pediatric Medicine department with diagnosis of FC were purposively recruited in the study. Data were collected by a trained physician from history, clinical examination, laboratory findings, treatment and outcome using a structured questionnaire.Results : Among the study children 41(51.3%) were between 6 months to 12 months with a male to female ratio was1.5:1. Forty-nine (61.2%) children had simple seizures, and 16 (20%) of the patients had family history of febrile seizures. In 70 (87.5%) cases the duration of seizure was less than 15 minutes and 75% patients had less than one attack within 24 hours of onset of fever. Upper respiratory tract infection was the most common (31%) cause of fever followed by unclassified in 21 (26%) cases. Complete blood count revealed leukocytosis in 49% cases, CRP raised in 30% cases while CSF study and ultrasonography of brain was normal in 30 cases and 10 cases. We could not perform any investigation to isolate possible causative virus. More than 90% per cent received intravenous broad-spectrum antibiotics and prophylactic anticonvulsant drugs during early days of hospitalization.Conclusion : In this study, Upper respiratory Tract infection was found as common cause of febrile convulsion. Duration of seizure was less than 15 minutes and Leukocytosis, raised CRP was identified and nearly all patients received broad-spectrum antibiotics during hospital stay.Northern International Medical College Journal Vol.7(1) Jul 2015: 101-104

Febrile Seizure in Children Attending a Tertiary Care Centre in Western Nepal: A Descriptive Cross-sectional Study

“…6,14 This study found 31.3% of children had recurrent febrile seizure, and it was comparable to the other studies which showed that the recurrence of febrile seizure was 33%, 32.5%. 9,17 However, the likelihood of recurrence in the present study is higher than few previous studies which noted that prevalence of recurrent seizure were 20.5%, 19.92%. 11,15 The difference could be due to the fact that environmental factors predisposes the children to have a fever that subsequently predispose to seizure among the genetically potential populations.…”

“…Many previous studies also reported URTI as the predominant cause. 9,13,14,17 The cause of URTI in our study presumed to be viral origin, based on their clinical characterizations and its course of illness as we did not have laboratory facility to isolate and identify virus. Following URTI, other causes are lower respiratory tract infection (19.2%), UTI (12.4%), nonspecific febrile illness and gastrointestinal infection.…”

“… 16 In contrast to our findings, other previous studies showed that family history of febrile seizure varies from 20% to 50% of the cases, which was higher than this study. 14 , 15 , 17 The difference could be because of the fact that parents may not be aware of their past illness and not able to recall as they were too young to remember the past medical illness. Besides all these, probably due to genetic potential in different populations could be the reason.…”

Clinical Profile, Radiological Resolution and Risk Factors Associated with Community Acquired Pneumonia

“…A study conducted on children hospitalized with pneumonia in Dhaulagiri Zonal Hospital of Nepal showed male to female ratio of 1.5:1 with a signifi cant proportion of the under-fi ve pneumonia burden. 9 The same fi nding of health disparity being associated with higher pneumonia cases among hospitalized male children than in female has been reported by the studies conducted in Bangladesh 10,11 , where the male female ration were 2:1 and 1.4:1 respectively. This could also be due to higher rates of care seeking for male children than for female children, giving strong preference for sons in the south Asian regions 12 .…”

Clinical and Laboratory Characteristics of Febrile Seizure in Children Presenting with Seizure

“…In laboratory analysis, Total leukocyctecount (TLC) was slight higher, other test of serum electrolytes, Calcium, Random blood glucose were normal in range, not siginificant in children with febrile seizure. Only 7.3% children had family h/o febrile seizure in our study, which was similar to other studies done by Shrestha D et al 1 , Shrestha et al 3 , Mwipopo EE, et al 13 Offringa H et al 14 Only 30.5% children had recurrence h/o in our study, which was inconsistent to study done by Shrestha D et al 1 , Shrestha et al 3 , Biswas R et al 15 which showed 33%, 31.3% and 32.5% respectively. Recurrence h/o was more common in male children in comparison to female children.…”