Clinical profile of neonates with respiratory distress

Bajad, Mamta; Goyal, Sanjay; Jain, Bhupesh

doi:10.18203/2349-3291.ijcp20162382

Cited by 16 publications

(34 citation statements)

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“…These findings have similarities with the Bajad et al in India who observed leading causes of respiratory distress to be hyaline membrane disease, birth asphyxia, septicemia/pneumonia, meconium aspiration syndrome, transient tachypnoea of newborn, in descending order. 6 However, while respiratory distress syndrome was significantly commoner among the preterms (p=0.001); birth asphyxia, transient tachpnoea of newborn (TTN) and meconium aspiration were statistically significant among the term babies (p at least 0.02). Therefore, the specific causes of NRD in the present study vary depending on the gestational age as also reported by previous authors.…”

Section: Discussionmentioning

confidence: 97%

“…18 Expectedly, respiratory distress syndrome (hyaline membrane diseases is a disease of preterms below 34 week gestation, rarely seen after 36 weeks. 6 Its prevalence decreases with increase maturity. It presents with tachypnoea, grunting and recession with or without cyanosis usually before 4 to 6 hours of life.…”

Section: Discussionmentioning

confidence: 99%

“…This is lower than findings of Bajad et al in India who reported 32% of all neonatal admissions; but higher than many other previous studies. [6][7][8][9] Abdelrahman et al in Sudan recorded neonatal respiratory distress (NRD) frequency rate of 4.83% among newborn delivered in the hospital but 56.5% among newborn admitted to NICU, Fedakar et al also reported 7% of neonatal admissions in Turkey, Kumar et al in India found overall incidence of 6.7%. [7][8][9] There is therefore, variation in the incidence of respiratory distress at different centres.…”

Section: Discussionmentioning

confidence: 99%

“…This finding is supported by previous studies. [6][7][8][9] The leading causes of neonatal respiratory distress were neonatal septicaemia, birth asphyxia, respiratory distress syndrome (hyaline membrane diseases) and transient tachypnoea of newborn in descending order. These findings have similarities with the Bajad et al in India who observed leading causes of respiratory distress to be hyaline membrane disease, birth asphyxia, septicemia/pneumonia, meconium aspiration syndrome, transient tachypnoea of newborn, in descending order.…”

Section: Discussionmentioning

confidence: 99%

“…Bajad et al also found perinatal asphyxia as a major cause of respiratory distress among Indian population, after hyaline membrane disease. 6 This is possibly a reflection of high prevalence of perinatal asphyxia in the developing countries.…”

Section: Discussionmentioning

confidence: 99%

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Determinants of outcome in newborns with respiratory distress in Osogbo, Nigeria

et al. 2017

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INTRODUCTIONRespiratory distress is one of the commonest presentations necessitating hospital admission of newborns.1 About 15% of term infants and 29% of late preterm infants admitted to the neonatal intensive care unit develop have significant respiratory symptoms; this is even higher for infants born before 34 weeks' gestation.2,3 The clinical presentations of respiratory distress in the newborn include difficulty with breathing (nasal flaring, recessions or retractions in the intercostal, subcostal, or supracostal spaces, grunting, head nodding); too fast breathing (tachypnoea -respiratory rate more than 60 breaths per minute); too slow or shallow breathing (bradypnoea -respiratory rate less than 30 per minute, apnea); noisy breathing (stertor, expiratory ABSTRACT Background: Respiratory distress is one of the commonest presentations necessitating hospital admission in newborn unit. Regardless of the cause, if not recognized and managed quickly, respiratory distress can escalate to apnoea, respiratory failure, cardiopulmonary arrest and death. Methods: A cross-sectional and descriptive study of newborns with respiratory distress admitted into the SCBU of LAUTECH Teaching Hospital, Osogbo, Nigeria. Respiratory distress was diagnosed by grunting, inspiratory stridor, nasal flaring and tachypnea (more than 60 breaths per minute), retractions in the intercostal, subcostal, or supracostal spaces and cyanosis. At admission, every neonate had a complete physical examination. Results: Of 625 babies admitted, 384 (61.4%) were males while 241 (38.6%) were females and 164 (26.2%) had respiratory distress. Respiratory distress was commoner among the preterms than term newborns.  2 = 44.7, p = 0.001. Leading causes of respiratory distress among the preterms were hyaline membrane disease, septicaemia, while among the term babies were perinatal asphyxia, transient tachypnoea of newborn and meconium aspiration. Sixty (36.6%) of the 164 babies with respiratory distress died. While 40.2% of the preterms died mainly from causes like hyaline membrane disease and septicaemia, 31.3% of term babies died from causes like perinatal asphyxia and meconium aspiration. Mortality from hyaline membrane disease was 46.9%, while perinatal asphyxia and meconium aspiration accounted for 38.9% and 40.0% respectively. Conclusions: Respiratory distress is therefore, a very common neonatal problem and it causes death of more than third of those affected. Emphasis should be geared towards reduction of preterm delivery, control of asphyxia and neonatal sepsis in order to reduce neonatal mortality in our environment.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%