Clinical Profile of Organophosphate Poisoning at a Teritary Care Teaching Hospital

Abstract

Background: The major occupation in India is cultivation, where pesticides are regularly used for farming. Consumption of organophosphate compound in developing countries like India causes severe adverse effects leading to morbidity and mortality due to their effortless availability and lack of knowledge. To control pests, weeds, or plant disease organophosphorus compounds are used as insecticides. Aim: To study the clinical profile of organophosphate poisoning (OP) on different organ systems of the body. Material and Methods: The present study is prospective observational study carried out in AMC ward of MGMH Warangal, 102 subjects were recruited for the study. Results: Pesticide poisoning was more common in males (75%) than females (25%). Majority of the patients were between the age group of 21-30. The most commonly involved OP compound was Chlorpyrifos. Among 102 patients, 54 patients experienced mild symptoms, 46 patients experienced with moderate symptoms and 2 patients were experienced with severe symptoms. Conclusion: OP poisoning is a serious debilitating condition in AMC requires intensive supportive care, treatment with antidote is necessary as it is affecting different organ systems of the body. As the severity of poisoning in patients of our work is mild to moderate, no extrapyramidal effects were observed.